用于伤口管理的现代聚合物伤口护理涂层

E. O. Medusheva, Y. Fidorovskaya, M. A. Shchedrina, N. D. Oltarzhevskaya
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引用次数: 0

摘要

伤口处理过程第一阶段的疼痛控制包括溶解化脓性坏死组织、控制病原微生物菌群和排出伤口分泌物所造成的伤口清洁。新型复合材料具有纺织品基底、基于生物多糖海藻酸钠的水凝胶成分以及固定活性成分--植物源蛋白水解酶木瓜蛋白酶和抗菌盐类银--这些因素都可以通过新型复合材料来实现。纳米银的生物合成及其以阳离子形式存在于组合物中,提高了疗效,并消除了因银浓度低而产生的毒性。
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A modern polymer based wound care coating for wound management
Pain management at phase 1 of the wound process includes wound cleaning due to the lysis of purulent-necrotic masses, control of the pathogenic microflora, and evacuation of wound discharge. These factors are achievable with a new composite depo-material having the textile base, hydrogel composition based on biopolysaccharide sodium alginate with immobilized active components – proteolytic enzyme of plant origin- papain and antimicrobial salt-like silver. Biosynthesis of silver nanoparticles and its presence in the composition in the cation form increases efficacy and eliminates toxicity of the treatment due to low silver concentration.
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