格勒西克县积极吸烟者的碳氧血红蛋白(COHB)和血红蛋白(HB)水平的关系

Roudhotin Nur Azizah, Ayu Puspitasari
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摘要

在社会中,吸烟习惯仍然经常出现在成年人、青少年甚至幼儿中。众所周知,这些习惯会对身体造成负面影响,甚至导致死亡。香烟中有许多化学物质会导致健康问题的症状,其中之一就是一氧化碳(CO)。一氧化碳是香烟燃烧产生的气体,被吸入后会进入肺部和血液。一氧化碳气体会在氧气与血红蛋白结合的相同位置与血红蛋白结合,从而形成碳氧血红蛋白(COHb)。之所以会出现这种情况,是因为 CO 与血红蛋白的结合力强于 O2 与血红蛋白的结合力。本研究的目的是分析 Gresik 地区活跃吸烟者的碳氧血红蛋白水平与血红蛋白水平之间的关系。本研究是一项分析性观察研究,采用横断面设计,于 2022 年 10 月至 2023 年 6 月在泗水 Poltekkes Kemenkes 医学检验技术系毒理学和血液学实验室进行。采用目的性抽样技术对 30 名活跃吸烟者进行了血液检测。结果显示,平均 COHb 水平为 0.89%;平均血红蛋白水平为 14.6 g/dL。数据结果使用 SPSS 程序进行了分析。这项研究的结论是,在格雷斯克地区的活跃吸烟者中,一氧化碳血红蛋白与血红蛋白之间没有关系。
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RELATIONSHIP OF CARBOXYHEMOGLOBIN (COHB) AND HEMOGLOBIN (HB) LEVELS IN ACTIVE SMOKERS IN GRESIK REGENCY
Smoking habits in society are still often found among adults, adolescents, and even young children. It is known that these habits have a negative impact on the body and can cause death. There are a number of chemicals in cigarettes that cause symptoms of health problems, one of which is carbon monoxide (CO). Carbon monoxide, in the form of a gas due to combustion from cigarettes, is inhaled and enters the lungs and the bloodstream. CO gas will bind hemoglobin in the same place where oxygen binds hemoglobin, thus forming carboxyhemoglobin (COHb). This can happen because the binding force of CO is stronger than the binding power of O2 on Hb. The purpose of this study was to analyze the relationship between Carboxyhemoglobin levels and Hemoglobin levels in active smokers in Gresik Regency. This study was an analytical observational study with a cross sectional design conducted at the Toxicology and Hematology Laboratory of the Department of Medical Laboratory Technology, Poltekkes Kemenkes Surabaya, from October 2022 to June 2023. Blood tests were carried out on 30 active smokers with purposive sampling techniques. The results showed an average COHb level of 0.89%; average hemoglobin level of 14.6 g/dL. The data results were analyzed using the SPSS program. The conclusion of this reseach was that there was no relationship between COHb and Hemoglobin in active smokers in Gresik Regency.
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