Josué Vazquez-Chavez, Brian A. Verdeja-Perdomo, M. A. Iglesias‐Arteaga
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引用次数: 0
摘要
摘要介绍了应用四组份 Ugi 反应合成五种具有修饰侧链的胆汁酸衍生物的过程，并给出了明确的结构特征、功能 1H NMR 信号的分配以及所有 13C{1H} NMR 化学位移。摘要介绍了应用四组分 Ugi 反应合成带有修饰侧链的五种胆汁酸衍生物的过程。介绍了 1H NMR 功能信号和所有 13C{1H} NMR 化学位移的明确结构特征和分配。
Synthesis and NMR characterization of Bile Acid Derivatives Bearing Ugi 4CR-Modified Side Chains
Abstract. The application of the four-component Ugi reaction for the synthesis of five bile acid derivatives bearing modified side chains is described. The unambiguous structural characterization and assignment of the functional 1H NMR signals and all 13C{1H} NMR chemical shifts are presented.
Resumen. Se describe la aplicación de la reacción de cuatro componentes de Ugi a la síntesis de cinco derivados de ácidos biliares que portan cadenas laterales modificadas. Se presenta la caracterización estructural inequívoca y la asignación de las señales funcionales de 1H RMN y de todos los desplazamientos químicos de 13C{1H} RMN.
期刊介绍：
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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