Danilo José Silva Moreira, Vinicius Faustino Lima de Oliveira, Juliana Brito da Fonseca, Karoline Rossi, S. Vasconcelos, Amanda Alves Fecury, Carla Viana Dendasck, Cláudio Alberto Gellis de Mattos Dias, Euzébio de Oliveira, Maria Helena Mendonça de Araújo
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引用次数: 0
摘要
IgG4 相关疾病(IgG4-Related Disease)是一种浆细胞淋巴增生性疾病,与 IgG4 水平升高和受影响结构中 IgG4 阳性细胞浸润有关。由于其表现范围广泛,诊断起来仍有困难。本研究旨在强调构成其病谱的主要临床表现。本研究采用定性方法,在 Embase、PubMed、SCIELO 和 Web of Science 等数据库中进行了综合描述性文献综述。本综述共收录了 38 篇文章。据观察,IgG4 相关疾病的临床表现多种多样,有文献报道涉及身体的所有器官和系统。受影响最大的器官是胰腺、眼眶、唾液腺和泪腺。值得注意的是,这些不同的表现会导致不同的临床反响,由于有可能影响到重要器官,因此会导致病情复杂化。
Spectrum of manifestations of IgG4-related disease: a literature review
IgG4-Related Disease is a plasma cell lymphoproliferative condition, associated with increased levels of IgG4 and infiltration of IgG4-positive cells in affected structures. Due to its broad spectrum of manifestations, there are still difficulties in its diagnosis. This study aims to highlight the main clinical manifestations that comprise its spectrum. It is an integrative, descriptive literature review with a qualitative approach, conducted in the databases Embase, PubMed, SCIELO, and Web of Science. Thirty-eight articles were included in this review. It is observed that IgG4-Related Disease has a variable clinical presentation, with reports in the literature of involvement in all organs and systems of the body. The most affected organs are the pancreas, ocular orbits, salivary, and lacrimal glands. It is noteworthy that this variety of manifestations results in different clinical repercussions, which can lead to complicated conditions due to the possibility of affecting vital organs.