冠状动脉血管造影候选者中冠状动脉异常的频率及其与动脉粥样硬化性冠状动脉狭窄的关系

Alireza Amirzadegan, Hassan Aghajani, Khosro Barkhordari, Mehdi Mehrani, Aylar Ahmadi, Azim Hedayatpour, Mohammad Sadeghian
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摘要

导言:鉴于冠状动脉异常患者动脉粥样硬化病变的重要性,本研究旨在评估两年内在德黑兰心脏中心接受冠状动脉造影术的冠状动脉异常患者动脉粥样硬化病变的发生率。研究方法在这项横断面研究中,所有接受冠状动脉造影术并被诊断为冠状动脉异常的患者均被纳入本研究(2018-2020 年)。然后确定并报告了患者中被检测出的异常、心血管风险因素以及是否存在冠状动脉狭窄的频率和频率百分比。结果在本研究评估的 79 名冠状动脉异常患者中,男性和女性分别为 43 人(54.4%)和 36 人(45.6%)。其中,39.2%的患者吸烟,10.1%的患者对阿片类药物成瘾。这些患者最常见的基础疾病是血脂异常、高血压和糖尿病,分别占 63%、49% 和 46%。此外,女性患高血压的比例更高(P=0.005)。共有 81.6% 的患者(所有患者的冠状动脉均异常)的冠状动脉存在粥样硬化性狭窄。冠状动脉异常频率最高的是来自右冠状窦的左侧环状动脉,占 29.1%;其他包括左主干缺失、冠状动脉瘘和来自左冠状窦的右冠状动脉,占 12.7%。结论在冠状动脉异常的患者中,动脉粥样硬化病变是常见病,这可能是导致这些患者心脏性猝死的重要原因。
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Frequency of Coronary Anomalies and Association with Atherosclerotic Coronary Stenoses in the Coronary Angiography Candidates
Introduction: Due to the importance of atherosclerotic changes in the patients with coronary anomalies, it was aimed to evaluate the prevalence of atherosclerotic changes in patients with coronary anomalies who underwent coronary angiography at Tehran Heart Center within two years. Methods: In this cross-sectional study, all the patients who underwent coronary angiography and were diagnosed with coronary artery anomalies were included in this study (2018-2020). The frequency and frequency percentage of the detected anomalies, cardiovascular risk factors and also the presence of coronary stenosis among the patients were then determined and reported. Results: Among 79 patients with coronary artery anomaly evaluated in this study, 43 (54.4%) and 36 (45.6) were male and female, respectively. Of these, 39.2% were smokers and 10.1% had an addiction to opioids. The most frequent baseline disease in these patients was dyslipidemia, hypertension, and diabetes mellitus with 63%, 49%, and 46%, respectively. Moreover, hypertension was more frequent in women (p=0.005). A total of 81.6% of the patients (all of them had abnormal coronary arteries) had atherosclerotic stenosis in their coronary arteries. The highest frequency of coronary abnormality was left circumflex from right coronary sinus with 29.1%; the others included absent left main, coronary fistula, and right coronary artery from left coronary sinus, which were 12.7%. Conclusion: In the patients with coronary artery anomalies, atherosclerotic changes were frequent prevalence, which can be an important cause of sudden cardiac death in these patients.
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