肝硬化心肌病:永远的热门话题

IF 4.7 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2024-01-01 DOI:10.2144/fsoa-2023-0110
Mona Boudabbous, R. Hammemi, H. Gdoura, L. Chtourou, M. Moalla, L. Mnif, A. Amouri, Leila Abid, N. Tahri
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引用次数: 0

摘要

肝硬化是慢性肝病肝纤维化发展的最后阶段。肝硬化伴有严重的血流动力学障碍,表现为高动力循环,可能并发特定的心脏受累或肝硬化心肌病,这是一种无声的临床症状,通常在肝病晚期才会出现症状。最近,根据心力衰竭的现代概念和知识提出了定义 CC 的新标准。尽管人们了解这种疾病背后的主要机制,但目前还没有针对肝硬化性心肌病的特殊治疗方法。肝硬化患者无症状心肌病的治疗方法与非肝硬化患者左心室衰竭的治疗方法类似。
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Cirrhotic cardiomyopathy: a subject that's always topical
Cirrhosis is the final stage in the development of hepatic fibrosis in chronic liver disease. It is associated with major hemodynamic disturbances defining the hyperdynamic circulation and may be complicated by specific cardiac involvement or cirrhotic cardiomyopathy which is a silent clinical condition that typically remains asymptomatic until the late stages of liver disease. Recently, new criteria defining CC, based on modern concepts and knowledge of heart failure, have been proposed. Despite knowledge of the main mechanisms behind this entity, there is no specific treatment available for cirrhotic cardiomyopathy. The management approach for symptomatic cardiomyopathy in cirrhotic patients is similar to that for left ventricular failure in non-cirrhotic individuals.
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
期刊介绍: ACS Applied Bio Materials is an interdisciplinary journal publishing original research covering all aspects of biomaterials and biointerfaces including and beyond the traditional biosensing, biomedical and therapeutic applications. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrates knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important bio applications. The journal is specifically interested in work that addresses the relationship between structure and function and assesses the stability and degradation of materials under relevant environmental and biological conditions.
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