三维打印技术在糖尿病医疗、制药和营养方面的应用

IF 4.3 Q1 ENDOCRINOLOGY & METABOLISM Diabetes & Metabolic Syndrome-Clinical Research & Reviews Pub Date : 2024-04-01 DOI:10.1016/j.dsx.2024.103002
Reza Amin , Sayed Mahdi Hossaeini Marashi , Seyyed Mohammad Reza Noori , Zeinab Alavi , Elaheh Dehghani , Reyhaneh Maleki , Mehdi Safdarian , Arash Rocky , Enayat Berizi , Seyyed Mohammad Amin Alemohammad , Setayesh Zamanpour , Seyyed Mohammad Ali Noori
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引用次数: 0

摘要

目的尽管有许多研究涉及三维打印(3D 打印)技术的各种特点及其在食品科学和疾病治疗中的应用,但尚未有研究调查 3D打印技术在糖尿病中的应用。因此,本研究集中探讨了三维打印技术在糖尿病治疗的营养、药物和医疗方面的应用及其影响。结果3D打印技术在放置细胞方面的高精度实现了精确的解剖控制,并为胰腺和β细胞的生物打印提供了可能。通过三维打印微针(MN)贴片进行透皮给药有利于糖尿病的治疗。三维打印技术为糖尿病(DM)的个性化医疗提供了支持。例如,它使制药公司能够为每位糖尿病患者生产独特剂量的药物。总之,将 3D 打印技术应用于糖尿病管理尚处于早期阶段,需要不断成熟和发展才能安全地用于人类。然而,近年来3D打印技术的飞速发展为糖尿病治疗带来了光明的前景。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Medical, pharmaceutical, and nutritional applications of 3D-printing technology in diabetes

Aims

Despite numerous studies covering the various features of three-dimensional printing (3D printing) technology, and its applications in food science and disease treatment, no study has yet been conducted to investigate applying 3D printing in diabetes. Therefore, the present study centers on the utilization and impact of 3D printing technology in relation to the nutritional, pharmaceutical, and medicinal facets of diabetes management. It highlights the latest advancements, and challenges in this field.

Methods

In this review, the articles focusing on the application and effect of 3D printing technology on medical, pharmaceutical, and nutritional aspects of diabetes management were collected from different databases.

Result

High precision of 3D printing in the placement of cells led to accurate anatomic control, and the possibility of bio-printing pancreas and β-cells. Transdermal drug delivery via 3D-printed microneedle (MN) patches was beneficial for the management of diabetes disease. 3D printing supported personalized medicine for Diabetes Mellitus (DM). For instance, it made it possible for pharmaceutical companies to manufacture unique doses of medications for every diabetic patient. Moreover, 3D printing allowed the food industry to produce high-fiber and sugar-free products for the individuals with DM.

Conclusions

In summary, applying 3D printing technology for diabetes management is in its early stages, and needs to be matured and developed to be safely used for humans. However, its rapid progress in recent years showed a bright future for the treatment of diabetes.

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来源期刊
CiteScore
22.90
自引率
2.00%
发文量
248
审稿时长
51 days
期刊介绍: Diabetes and Metabolic Syndrome: Clinical Research and Reviews is the official journal of DiabetesIndia. It aims to provide a global platform for healthcare professionals, diabetes educators, and other stakeholders to submit their research on diabetes care. Types of Publications: Diabetes and Metabolic Syndrome: Clinical Research and Reviews publishes peer-reviewed original articles, reviews, short communications, case reports, letters to the Editor, and expert comments. Reviews and mini-reviews are particularly welcomed for areas within endocrinology undergoing rapid changes.
期刊最新文献
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