雌激素对n -亚硝基二甲胺诱导的雌性蟾蜍肝肿瘤的增强作用。

Archiv fur Geschwulstforschung Pub Date : 1989-01-01

S A Sakr, M M el-Mofty, A M Mohamed

{"title":"雌激素对n -亚硝基二甲胺诱导的雌性蟾蜍肝肿瘤的增强作用。","authors":"S A Sakr, M M el-Mofty, A M Mohamed","doi":"","DOIUrl":null,"url":null,"abstract":"The effect of oestrone on hepatic tumours induced in the female toads Bufo regularis by N-nitrosodimethylamine (DMNA) was evaluated. Injecting the toads with DMNA induced hepatocellular carcinomas in 17% comparable with 23% in toads injected with DMNA plus oestrone. These results show that oestrone insignificantly enhanced the tumour formation. Oestrone alone induced hepatic tumours in only 4 cases and was considered as a weak initiator.","PeriodicalId":8274,"journal":{"name":"Archiv fur Geschwulstforschung","volume":"59 1","pages":"7-10"},"PeriodicalIF":0.0000,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Enhancement of hepatic tumors induced by N-nitrosodimethylamine in female toads Bufo regularis by oestrone.\",\"authors\":\"S A Sakr, M M el-Mofty, A M Mohamed\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The effect of oestrone on hepatic tumours induced in the female toads Bufo regularis by N-nitrosodimethylamine (DMNA) was evaluated. Injecting the toads with DMNA induced hepatocellular carcinomas in 17% comparable with 23% in toads injected with DMNA plus oestrone. These results show that oestrone insignificantly enhanced the tumour formation. Oestrone alone induced hepatic tumours in only 4 cases and was considered as a weak initiator.\",\"PeriodicalId\":8274,\"journal\":{\"name\":\"Archiv fur Geschwulstforschung\",\"volume\":\"59 1\",\"pages\":\"7-10\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1989-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Archiv fur Geschwulstforschung\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archiv fur Geschwulstforschung","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

摘要

研究了雌酮对n -亚硝基二甲胺(DMNA)诱导的雌性蟾蜍肝肿瘤的影响。注射DMNA诱导肝细胞癌的蟾蜍为17%，而注射DMNA加雌酮的蟾蜍为23%。这些结果表明，雌激素对肿瘤形成的促进作用不显著。单用雌酮诱导肝肿瘤仅4例，被认为是弱引发剂。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

微信好友朋友圈 QQ好友复制链接

本刊更多论文

Enhancement of hepatic tumors induced by N-nitrosodimethylamine in female toads Bufo regularis by oestrone.

The effect of oestrone on hepatic tumours induced in the female toads Bufo regularis by N-nitrosodimethylamine (DMNA) was evaluated. Injecting the toads with DMNA induced hepatocellular carcinomas in 17% comparable with 23% in toads injected with DMNA plus oestrone. These results show that oestrone insignificantly enhanced the tumour formation. Oestrone alone induced hepatic tumours in only 4 cases and was considered as a weak initiator.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Archiv fur Geschwulstforschung

自引率

0.00%

发文量