{"title":"儿科重症监护室患者使用 BioFire Pneumonia plus Panel 对支气管样本进行盲测的诊断准确性及其对早期适应抗菌疗法的影响：一项前瞻性观察研究。","authors":"Guillaume Geslain, Aurélie Cointe, Jérôme Naudin, Stéphane Dauger, Nora Poey, Justine Pages, Enora Le Roux, Stéphane Bonacorsi","doi":"10.1097/inf.0000000000004349","DOIUrl":null,"url":null,"abstract":"Community-acquired and nosocomial lower-respiratory-tract infections in critically ill pediatric patients require early appropriate antibiotic therapy to optimize outcomes. Using blind bronchial samples, we assessed the diagnostic performance of the rapid-multiplex polymerase chain reaction (PCR) assay BioFire Pneumonia plus Panel vs. reference standard culturing with antimicrobial susceptibility testing.","PeriodicalId":501652,"journal":{"name":"The Pediatric Infectious Disease Journal","volume":"18 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Diagnostic Accuracy of Blind Bronchial Sample Testing by BioFire Pneumonia plus Panel in Pediatric Intensive Care Unit Patients and Its Impact in Early Adaptation of Antimicrobial Therapy: A Prospective Observational Study.\",\"authors\":\"Guillaume Geslain, Aurélie Cointe, Jérôme Naudin, Stéphane Dauger, Nora Poey, Justine Pages, Enora Le Roux, Stéphane Bonacorsi\",\"doi\":\"10.1097/inf.0000000000004349\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Community-acquired and nosocomial lower-respiratory-tract infections in critically ill pediatric patients require early appropriate antibiotic therapy to optimize outcomes. Using blind bronchial samples, we assessed the diagnostic performance of the rapid-multiplex polymerase chain reaction (PCR) assay BioFire Pneumonia plus Panel vs. reference standard culturing with antimicrobial susceptibility testing.\",\"PeriodicalId\":501652,\"journal\":{\"name\":\"The Pediatric Infectious Disease Journal\",\"volume\":\"18 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-04-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Pediatric Infectious Disease Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1097/inf.0000000000004349\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Pediatric Infectious Disease Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1097/inf.0000000000004349","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
儿科危重病人的社区获得性和医院内下呼吸道感染需要尽早接受适当的抗生素治疗，以优化治疗效果。我们使用盲支气管样本，评估了快速多重聚合酶链反应（PCR）测定 BioFire Pneumonia plus Panel 与抗菌药物药敏试验参考标准培养法的诊断性能。
Diagnostic Accuracy of Blind Bronchial Sample Testing by BioFire Pneumonia plus Panel in Pediatric Intensive Care Unit Patients and Its Impact in Early Adaptation of Antimicrobial Therapy: A Prospective Observational Study.
Community-acquired and nosocomial lower-respiratory-tract infections in critically ill pediatric patients require early appropriate antibiotic therapy to optimize outcomes. Using blind bronchial samples, we assessed the diagnostic performance of the rapid-multiplex polymerase chain reaction (PCR) assay BioFire Pneumonia plus Panel vs. reference standard culturing with antimicrobial susceptibility testing.
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