生物工程蛋白质作为核酸载体的复兴

IF 4 2区 化学 Q1 BIOCHEMICAL RESEARCH METHODS Bioconjugate Chemistry Bioconjugate Pub Date : 2024-04-15 DOI:10.1021/acs.bioconjchem.4c00079
David Scherer, Michael Burger* and Jean-Christophe Leroux*, 
{"title":"生物工程蛋白质作为核酸载体的复兴","authors":"David Scherer, Michael Burger* and Jean-Christophe Leroux*, ","doi":"10.1021/acs.bioconjchem.4c00079","DOIUrl":null,"url":null,"abstract":"","PeriodicalId":29,"journal":{"name":"Bioconjugate Chemistry Bioconjugate","volume":null,"pages":null},"PeriodicalIF":4.0000,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acs.bioconjchem.4c00079","citationCount":"0","resultStr":"{\"title\":\"Revival of Bioengineered Proteins as Carriers for Nucleic Acids\",\"authors\":\"David Scherer, Michael Burger* and Jean-Christophe Leroux*, \",\"doi\":\"10.1021/acs.bioconjchem.4c00079\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\",\"PeriodicalId\":29,\"journal\":{\"name\":\"Bioconjugate Chemistry Bioconjugate\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":4.0000,\"publicationDate\":\"2024-04-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://pubs.acs.org/doi/epdf/10.1021/acs.bioconjchem.4c00079\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Bioconjugate Chemistry Bioconjugate\",\"FirstCategoryId\":\"1\",\"ListUrlMain\":\"https://pubs.acs.org/doi/10.1021/acs.bioconjchem.4c00079\",\"RegionNum\":2,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"BIOCHEMICAL RESEARCH METHODS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bioconjugate Chemistry Bioconjugate","FirstCategoryId":"1","ListUrlMain":"https://pubs.acs.org/doi/10.1021/acs.bioconjchem.4c00079","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}
引用次数: 0

摘要

图 1.纳米载体压实核酸,使其不受体液影响,并允许其被靶细胞转运和吸收(A)。载体的内吞可以自发发生,也可以由细胞受体诱导(B)。随后,核酸必须逃离内质体才能到达细胞质(C、D)。最后,DNA 需要受到保护并被输送到细胞核(E)。由 BioRender.com 制作。感谢欧盟地平线 2020 研究与创新计划下的欧洲研究理事会(ERC)提供的资金(拨款号:884505)。本文引用了 78 篇其他出版物。本文尚未被其他出版物引用。图 1.纳米载体压实核酸,使其不受体液影响,并允许其被靶细胞转运和吸收(A)。载体的内吞可以自发发生,也可以由细胞受体诱导(B)。随后,核酸必须逃离内质体才能到达细胞质(C、D)。最后,DNA 需要受到保护并被输送到细胞核(E)。用 BioRender.com 制作。本文参考了 78 篇其他出版物。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

摘要图片

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Revival of Bioengineered Proteins as Carriers for Nucleic Acids
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
9.00
自引率
2.10%
发文量
236
审稿时长
1.4 months
期刊介绍: Bioconjugate Chemistry invites original contributions on all research at the interface between man-made and biological materials. The mission of the journal is to communicate to advances in fields including therapeutic delivery, imaging, bionanotechnology, and synthetic biology. Bioconjugate Chemistry is intended to provide a forum for presentation of research relevant to all aspects of bioconjugates, including the preparation, properties and applications of biomolecular conjugates.
期刊最新文献
Equimolar Cross-Coupling Using Reactive Coiled Coils for Covalent Protein Assemblies. Identification of a Novel Transasparaginase Activity of Bacillus subtilis (bTG) for Sequence-Specific Bioconjugation. Linker and Conjugation Site Synergy in Antibody-Drug Conjugates: Impacts on Biological Activity. Poly(malic acid) Nanoconjugates of Pyrazinoic Acid for Lung Delivery in the Treatment of Tuberculosis. Tyrosinase-Mediated Conjugation for Antigen Display on Ferritin Nanoparticles.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1