α-突触核蛋白与线粒体的相互作用是麦拉宁诱导 SH-SY5Y 细胞铁性死亡的最终机制

IF 3.6 3区 生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY Free Radical Research Pub Date : 2024-04-04 DOI:10.1080/10715762.2024.2336563
Upasana Ganguly, Sukhpal Singh, Aritri Bir, Arindam Ghosh, Sankha Shubhra Chakrabarti, Reena V Saini, Luciano Saso, Marco Bisaglia, Sasanka Chakrabarti
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引用次数: 0

摘要

铁突变是一种铁依赖性调节细胞死亡形式,伴随着活性氧和脂质氧化产物的积累以及典型的形态学变化。
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Alpha-synuclein interaction with mitochondria is the final mechanism of ferroptotic death induced by erastin in SH-SY5Y cells
Ferroptosis has been characterized as a form of iron-dependent regulated cell death accompanied by an accumulation of reactive oxygen species and lipid oxidation products along with typical morphol...
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来源期刊
Free Radical Research
Free Radical Research 生物-生化与分子生物学
CiteScore
6.70
自引率
0.00%
发文量
47
审稿时长
3 months
期刊介绍: Free Radical Research publishes high-quality research papers, hypotheses and reviews in free radicals and other reactive species in biological, clinical, environmental and other systems; redox signalling; antioxidants, including diet-derived antioxidants and other relevant aspects of human nutrition; and oxidative damage, mechanisms and measurement.
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Cutting-edge insights into Helicobacter research. Protective effect of alpha-tocopherol on lipogenesis and oxysterol production in hypercholesterolemia-induced nonalcoholic steatohepatitis. Redox factors in the antioxidant activity of nitroxides toward DNA guanyl and 2-deoxyribose-peroxyl radicals. The impact of hyperbaric oxygen therapy on the redox balance of patients with diabetic foot syndrome. Metformin suppresses metabolic dysfunction-associated fatty liver disease by ferroptosis and apoptosis via activation of oxidative stress.
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