利多卡因能减轻注射皮质类固醇时的疼痛强度吗?双盲随机对照等效试验

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2024-04-20 DOI:10.1177/17531934241245036
Teun Teunis, George E. Sayegh, Amir Fatehi, David Ring, Gregg Vagner, Lee Reichel
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引用次数: 0

摘要

在限制皮质类固醇注射不适感的策略中,一种是在不使用利多卡因的情况下进行注射,以减少注射总量并避免酸性。在一项贝叶斯试验中,接受皮质类固醇注射的成人被随机分配接受 0.5 毫升的曲安奈德和 0.5 毫升的利多卡因。进行连续分析,直到 0-10 数字评分量表中疼痛强度出现或不出现 1.0 点差异的概率达到 95%。注射利多卡因可使注射时的疼痛强度中位数降低 2.4 分,95% 的概率至少降低 1 分。在 90% 的重复分析中(36/40),95% 的概率得到了证实。利多卡因可降低手部和腕部皮质类固醇注射时的即时疼痛强度:I
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Does lidocaine reduce pain intensity during corticosteroid injection? A double-blind randomized controlled equivalence trial
Of the strategies considered to limit the discomfort of corticosteroid injection, one is to inject without lidocaine to reduce the total volume and avoid acidity. In a Bayesian trial, adults receiving corticosteroid injections were randomized to receive 0.5 mL of triamcinolone with or without 0.5 mL of lidocaine. Serial analysis was performed until a 95% probability of presence or absence of a 1.0-point difference in pain intensity on the 0–10 Numerical Rating Scale was reached. Injections with lidocaine were associated with a median of 2.4-point lower pain intensity during injection with a 95% probability of at least a 1-point reduction. The 95% probability was confirmed in 90% of the repeated analysis (36/40). Lidocaine is associated with lower immediate pain intensity during corticosteroid injection for hand and wrist conditions.Level of evidence: I
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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