一名免疫功能正常的波利尼西亚男子口腔中发生的典型卡波西肉瘤

Leon Kong , Abdul-Kader Ebrahim , Duncan Lamont
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引用次数: 0

摘要

卡波西肉瘤(KS)是一种不常见的血管增生性肿瘤。典型的卡波西肉瘤很少发生在头颈部。KS 的病原体是人类疱疹病毒 8 型(HHV-8)感染。在免疫功能正常的人群中,KS 的 HHV-8 血清阳性率往往很高,其中包括地中海人和犹太人。关于免疫功能正常的波利尼西亚人感染 KS 的描述几乎不存在。其中一个原因可能是生活在大洋洲地区的原住民在地理和文化上都相对偏远。最近有报道称,在邻近波利尼西亚的瓦努阿图、新喀里多尼亚和巴布亚新几内亚的美拉尼西亚土著居民中,HHV-8 血清阳性率很高。本文首次描述了波利尼西亚血统的免疫功能正常患者口腔中分离出的典型 KS,并强调了进一步研究的必要性,以明确该地区出现 KS 的风险。
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Classic Kaposi's sarcoma of the oral cavity occurring in an immunocompetent Polynesian man

Kaposi's sarcoma (KS) is an uncommon angioproliferative tumour. In its classic form, it rarely affects the head and neck. The etiologic agent in KS is Human Herpesvirus type-8 (HHV-8) infection. Populations in which KS occurs in the setting of immunocompetence tend to have high rates of seropositivity for HHV-8, including Mediterranean and Jewish people. Descriptions of KS in immunocompetent Polynesian individuals are almost non-existent. A reason for this may be the relative inaccessibility, both geographically and culturally, of indigenous peoples living in the Oceanic area. High rates of HHV-8 seropositivity have recently been reported in indigenous Melanesian populations of Vanuatu, New Caledonia and Papua New Guinea, a region neighbouring Polynesia. This paper is the first to describe classic KS isolated to the oral cavity in an immunocompetent patient of Polynesian ancestry and highlights the need for further research to clarify the risk of KS emerging in this region.

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来源期刊
Oral and Maxillofacial Surgery Cases
Oral and Maxillofacial Surgery Cases Medicine-Otorhinolaryngology
CiteScore
0.60
自引率
0.00%
发文量
43
审稿时长
69 days
期刊介绍: Oral and Maxillofacial Surgery Cases is a surgical journal dedicated to publishing case reports and case series only which must be original, educational, rare conditions or findings, or clinically interesting to an international audience of surgeons and clinicians. Case series can be prospective or retrospective and examine the outcomes of management or mechanisms in more than one patient. Case reports may include new or modified methodology and treatment, uncommon findings, and mechanisms. All case reports and case series will be peer reviewed for acceptance for publication in the Journal.
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