通过核心针活检确诊的多器官 IgG4 相关性浆液性腺炎:病例报告

Shishuo Ma , Xiaojuan He , Weijia Huang
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摘要

由于免疫球蛋白 G4 相关性浆液性腺炎(IgG4-RS)的罕见性以及与其他形式的硬化性浆液性腺炎的相似性,对其进行诊断仍具有挑战性。关于活检方法的争议一直存在。我们报告了一例主要唾液腺硬化性唾液腺炎、胰腺炎、血清 IgG4 水平升高的病例,核心针活检(CNB)发现淋巴浆细胞浸润。本病例报告旨在提高人们对在疑似 IgG4-RS 病例中可能使用 CNB 的认识,与开放活检相比,CNB 可最大限度地降低相关风险。
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Multi-organ IgG4-related sialadenitis diagnosed via core needle biopsy: A case report

Diagnosing Immunoglobulin G4-related sialadenitis (IgG4-RS) remains challenging due to its rarity and similarity to other forms of sclerosing sialadenitis. Controversies persist regarding biopsy approaches. We presented a case with sclerosing sialadenitis in the major salivary glands, pancreatitis, elevated serum IgG4 levels, and core needle biopsy (CNB) revealed lymphoplasmacytic infiltration. This case report aims to raise awareness of the potential use of CNB in suspected IgG4-RS cases, minimizing associated risks compared to open biopsy.

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