来自吉它根(Willughbeia coriacea Wall.)的异黄酮类化合物

Jamarlia Aprenesya, Puji Ardiningsih., dan Rudiyansyah
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引用次数: 0

摘要

Gitaan(Willughbeia coriacea Wall.)是一种生长在加里曼丹森林中的野生特有植物。传统上,达雅克(Dayak)部落将这种植物的部分成分用于叉叉药。然而,关于这种植物的次生代谢物和生物活性,尤其是黄酮类化合物的信息报道很少。本研究通过光谱分析确定了吉塔安根乙酸乙酯馏分中黄酮类化合物的结构。根据核磁共振分析(包括 DART-HRMS 数据)以及与文献的比较,从 gitaan 根的乙酸乙酯馏分中获得的异黄酮类化合物是福莫尼定。
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Senyawa Isoflavonoid dari Akar Gitaan (Willughbeia coriacea Wall.)
Gitaan (Willughbeia coriacea Wall.) is an endemic plant that grows wild in the forests of Kalimantan. Traditionally, parts of this plant have been applied for fork-lore medication in Dayak tribe. However, scarce information both for secondary metabolites and biological activities of this plant has been reported, especially for flavonoids. This research was conducted to determine structure of flavonoid from ethyl acetate fraction of gitaan roots by spectroscopy analysis. The ethyl acetate fraction was purified by several chromatography techiques in order to isolate compound 1. On the basis of NMR analysis including DART-HRMS data and comparison with literature, an isoflavonoid obtained from the ethyl acetate fraction of gitaan roots is formononetin.
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发文量
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审稿时长
12 weeks
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