O. N. Egorova, G. M. Tarasova, B. Issaeva, A. Datsina, D. S. Dilmanova, S. M. Issaeva, M. G. Nogaeva, A. G. Issaeva, A. S. Amanzholova, M. Saparbayeva, A. Atasheva, A. B. Kanapina
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引用次数: 0
摘要
与抗中性粒细胞胞浆抗体（ANCA）相关的血管炎是一组全身性自身免疫性疾病，其特点是以小血管壁坏死性病变为主，并存在抗蛋白酶 3 或髓过氧化物酶的 ANCA。然而，在其他疾病中也可观察到 ANCA 水平升高，包括自身免疫性疾病、恶性疾病和感染性疾病，这就使临床和实验室数据的解释变得复杂，需要进行鉴别诊断。
On the problem of differential diagnosis in the detection of antineutrophil cytoplasmic antibodies
Vasculitides associated with antineutrophil cytoplasmic antibodies (ANCA) are a group of systemic autoimmune diseases characterized by necrotizing lesions of the walls of predominantly small vessels and the presence of ANCA against proteinase 3 or myeloperoxidase. However, an increase in ANCA levels can also be observed in other diseases, including autoimmune, malignant and infectious diseases, which complicates the interpretation of clinical and laboratory data and requires a differential diagnosis.
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