使用细胞离心机和普通离心机进行体液细胞学比较研究

Madhuri Roy, D. Wakkar
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摘要

体腔液细胞学研究有助于检测多种细菌、真菌或病毒性疾病以及恶性肿瘤。本研究的重点是恶性细胞的类型、分布和形态保存、细胞产量以及阳性病例的结果比较:评估细胞离心机(Pr0Cyt.LED4)在三级医院细胞诊断中的实用性、灵敏度,并与传统离心机的结果进行比较。我们使用腹水、胸水、脑脊液和其他体腔液样本进行了一项前瞻性调查,这些样本被平均分成两份,在普通离心机和细胞离心机中以预定参数同时离心。结果表明,两种方法在统计学上有显著差异,P 值小于 0.05。根据这项比较研究,细胞离心机制备方法在细胞产量、细胞形态的完好保存以及拾取恶性细胞的能力等方面均优于普通离心机,从而提高了其灵敏度,改善了其诊断用途。
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Comparative study of body fluid cytology using cytocentrifuge and ordinary centrifuge
The detection of numerous bacterial, fungal, or viral illnesses as well as malignancies is aided by the cytologic study of bodily cavity fluids. The focus of this study is on the type of malignant cells, their distribution and preservation of morphology, cell yield, and comparing the outcomes for positive cases.: To assess the utility, sensitivity and compare the results obtained by cytocentrifuge (Pr0Cyt.LED4) with those of conventional centrifuge in cytodiagnosis in Tertiary Care Hospital. A prospective investigation was carried out using ascitic, pleural, cerebrospinal, and other bodily cavity fluid samples that were split equally and centrifuged simultaneously at predetermined parameters in an ordinary centrifuge and a cytocentrifuge.For cytodiagnosis, 100 samples were examined. With a p-value less than 0.05, the results demonstrated a statistically significant difference between the two approaches. According to this comparison study, the cytocentrifuge preparation outperforms the ordinary centrifuge in terms of cell yield, well-preserved cell morphology, and ability to pick up malignant cells, hence enhancing its sensitivity and improving its diagnostic use.
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