胸骨软骨肉瘤:一种罕见且具有挑战性的实体瘤

Q3 Medicine Ethiopian Medical Journal Pub Date : 2024-04-15 DOI:10.4314/emj.v62i2.9
A. Guiga, Wissal ben Yahia, Atef Benabdelkader, Amel Amara, Maissa Thabet, Maissa Omrani, Ansar Mefteh, Bechir Ben Radhia, A. Atig, N. Ghannouchi
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引用次数: 0

摘要

背景:软骨肉瘤是一种比较常见的原发性恶性骨肿瘤,而胸骨是一个不常见的部位。当这种肿瘤发生在胸骨时,临床医生会遇到复杂的诊断和治疗问题。事实上,由于胸骨位置可能发生局部侵袭、转移和预后不良,因此值得关注。然而,由于报道的病例数量有限,而且对胸骨软骨肉瘤的专门研究很少,因此最佳治疗策略仍存在争议:一名 82 岁的男性,因胸骨疼痛就诊。CT 扫描显示胸骨连续性丧失,胸骨体出现破坏性混合病变,皮质广泛溶解,邻近软组织浸润。活检确诊为二级软骨肉瘤,无转移迹象。讨论:胸骨软骨肉瘤是一种比较常见的原发性恶性骨肿瘤,包括X光、CT、MRI和PET扫描在内的影像学技术在诊断中起着至关重要的作用。该肿瘤的治疗包括手术切除,目的是彻底切除肿瘤。预后取决于癌症分期、组织学分级、肿瘤大小、有无转移以及对治疗的反应等因素。肿瘤分级高、体积大、有转移灶的预后较差。
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Chondrosarcoma of the sternum: A rare and challenging entity
Background: Chondrosarcoma is a relatively common primary malignant bone tumor, with the sternum being an unusual location. When this tumor arises in the sternum, clinicians encounter diagnostic and therapeutic complexities. Indeed, the sternal location warrants attention due to its potential for local invasion, metastasis, and poor prognosis. Nonetheless, optimal treatment strategies remain contentious, hampered by the limited number of reported cases and a scarcity of dedicated research on sternal chondrosarcomas.Case presentation: A 82-year-old male, presented with sternal pain. CT scan, revealed loss of sternal continuity and a destructive mixed lesion involving the sternal body with extensive cortical lysis and infiltration of adjacent soft tissues. A biopsy confirmed the diagnosis of grade II chondrosarcoma without evidence of metastasis. The patient underwent surgical resection due to the absence of metastasis.Discussion: sternal chondrosarcoma is a relatively frequent primary malignant bone tumor.Imaging techniques, including X-ray, CT, MRI, and PET scans, play a crucial role in diagnosis. Management of this tumor involves surgical resection with the goal of complete tumor removal. Prognosis depends on factors such as cancer stage, histological grade, tumor size, presence of metastases, and response to treatment. High grade and larger tumors, the presence of metastases are associated with a poorer prognosis.
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来源期刊
Ethiopian Medical Journal
Ethiopian Medical Journal Medicine-Medicine (all)
CiteScore
0.40
自引率
0.00%
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0
期刊介绍: The Ethiopian Medical Journal (EMJ) is the official Journal of the Ethiopian Medical Association (EMA) and devoted to the advancement and dissemination of knowledge pertaining to the broad field of medicine in Ethiopia and other developing countries. Prospective contributors to the Journal should take note of the instructions of Manuscript preparation and submission to EMJ as outlined below.
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