伊拉克早孕流产妇女的柯西氏菌感染率

Noor Hasan, Baydaa Hameed, Abdulkarreem Abbas, Mamdouh Mohamed Elbahnasawy
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摘要

Q热是一种由动物感染烧伤柯西氏杆菌(CB)引起的细菌性疾病。众所周知,感染 Q 热的小反刍动物会失去婴儿。人们认为,如果孕妇在怀孕期间感染Q热或感染复发,妊娠结果也会很糟糕。这项研究探讨了Q热的血清学结果与早孕损失(EPL)之间的联系。2022 年 9 月至 12 月,在巴格达(包括 Madinat Al-Imamain Al-Kadhmain 教学医院和 Abu Ghraib 医院)开展了多中心病例对照研究。共有 90 名妇女参加了此次调查。其中 60 名妇女因宫内妊娠无法存活而导致早孕流产。另外 30 名妇女为年龄、孕周相当的受试者,健康受试者为对照组。 使用商业酶联免疫吸附试验(ELISA)对血清样本进行CB抗体筛查。通过酶联免疫吸附试验,有 3 个病例(5%)的 CB 检测呈阳性。研究显示,不良妊娠结局与 Q 热血清学阳性之间没有关联。根据CB阳性病例的检测结果,年龄和流产史与烧伤弧菌血清阳性无明显关联。
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The incidence of coxiella infection in Iraqi women with early pregnancy loss
Query fever is a bacterial disease resulting from Coxiella burnetii (CB) infection in animals. It is well known that small ruminants who get Q fever lose their babies. People think pregnant women may also have lousy gestation results if they get the infection or the infection comes back to life during pregnancy. This study looks at how serologic results of Q fever and early pregnancy loss (EPL) are linked. In Baghdad, including Madinat Al-Imamain Al-Kadhmain Teaching Hospital and Abu Ghraib Hospital, multicenter case-control research was conducted from September to December 2022. A total of 90 women were enrolled in this investigation. Sixty clinically suffered from early pregnancy loss by having a nonviable intrauterine pregnancy. The other 30 women were subjects of comparable age, the week of pregnancy, and the healthy subjects as controls.  Using a commercial enzyme-linked immunosorbent assay (ELISA), serum samples were screened for antibodies against CB. Three (5%) cases tested positive for CB by ELISA. The study reveals no association between adverse gestation outcomes and positive Q fever serology. Age and abortion history were not significantly correlated with C. burnetii seropositivity, according to the findings of CB cases that tested positive results.
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