肝脏病变疑似恶性肿瘤患者的组织病理学结果与断层扫描结果的相关性

Luis P. Valencia Montiel, Jorge R. Hernández Santos, Arturo García-Galicia, Álvaro J. Montiel-Jarquín, Diana López García, Maricarmen Tapia Venancio, Nancy R. Bertado-Ramírez
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摘要

导言。肝癌是全球第七大常见肿瘤,也是癌症直接导致死亡的第二大原因。在墨西哥,肝癌的发病率占总人口的 3.9%。虽然计算机断层扫描(CT)是首选的影像学检查方法,但最终诊断还是要通过对病灶进行解剖病理学检查来确定。目标:将计算机断层扫描结果与病理解剖结果相联系。在 USG 引导下对怀疑有恶性肿瘤的肝脏病变患者进行活检,将断层扫描结果与组织病理学结果进行对比。方法。描述性、相关性、追溯性、同种统计学和单中心研究。研究时间为 2021 年 9 月至 2022 年 2 月。选取 18 岁以上、肝脏病变疑似恶性肿瘤的患者,进行计算机轴向断层扫描和超声引导下活检。采用 Shapiro Wilk 检验(正态性),并用卡方分析分类变量的相关性。结果24名患者接受了断层扫描和病灶活检,发现病灶平均大小为2.39厘米。断层扫描诊断与组织病理学确诊之间的相关性结果没有统计学意义,P=0.069。结论。在提示恶性肿瘤的肝脏病变中,组织病理学研究和断层扫描结果之间没有发现明显的相关性。
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Correlation of histopathological results and tomographic findings in patients with liver lesions suspicious for malignancy
Introduction. Liver cancer is the seventh most common neoplasm worldwide and the second cause of mortality directly associated with cancer. In Mexico it has an incidence of 3.9% in the entire population. Although computed tomography (CT) is the imaging study of choice, the final diagnosis is established with the anatomopathological study of the lesion. Objective. Correlate the tomographic findings with the histopathological result in patients with liver lesions with suspicion of malignancy, who underwent USG-guided biopsy. Methods. Descriptive, correlation, retrolective, homodemographic and single-center study. The study period was from September 2021 to February 2022. Patients older than 18 years with liver lesions suspicious of malignancy were selected and underwent Computed Axial Tomography and ultrasound-guided biopsy. Shapiro Wilk tests (for normality) were used and chi-square was used for an analysis of association of categorical variables. Results. Twenty-four patients were included, who underwent Tomography and lesion biopsy, finding an average size of lesions of 2.39cm. The results of the correlation between the tomographic diagnosis and the definitive histopathological diagnosis did not have statistical significance p=0.069. Conclusion. No significant correlation was found between the histopathological study and tomographic findings in liver lesions suggestive of malignancy.
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