伊拉克克里米亚-刚果出血热回顾性研究

Doaa Adnan Shaker, Muna Tawfeeq Abd, Nawar Jassim Alsalih, Sinan Ghazi Mahdi, Mohenned Alsaadawi, Ihab Raqeeb Aakef, Tareq Jafaar Aljandeel
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摘要

背景:CCHF通过蜱虫叮咬和直接接触感染患者或病毒动物的组织或血液传播。本研究旨在确定 2015 年至 2019 年期间伊拉克的 CCHF 发生情况。研究方法:本研究是一项回顾性和描述性横断面研究。它结合伊拉克传染病控制中心(CDC)/动物传染病科报告的 2015-2019 年间一些流行病学和人口统计学数据,对伊拉克 CCHF 的发生情况进行了核准。结果:在 206 例疑似病例中,只有 17 例被确诊为 CCHF,2015 年和 2018 年的总致死率分别为 52%、25% 和 80%。然而,2016 年、2017 年和 2019 年均无死亡病例报告。患者的平均年龄为(33 岁± 18 SD),以男性为主(76%)。此外,屠夫、动物交易者、增益者、家庭主妇、学生和儿童的风险组别分别为 29%、23%、18%、12% 和 6%。结论应采取严格的预防措施和精确的监测来控制该疾病,并通过改善 CCHF 的诊断和治疗来保护社区。作者建议今后再开展一项研究,对伊拉克的 CCHFV 进行基因分型和测序。关键词:克里米亚-刚果出血热克里米亚-刚果出血热;伊拉克;蜱虫。
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A retrospective study of Crimean-Congo hemorrhagic fever in Iraq
Background: CCHF is transmitted via ticks biting and directly by contact with tissue or blood of infected patients or viremicanimals. This study intends to determine the occurrence of CCHF in Iraq between 2015 and 2019. Methods: This study was designed as a retrospective and descriptive cross-sectional study. It was approved the occurrence ofCCHF in Iraq with relation to some epidemiological and demographic data reported in the Iraqi Communicable Diseases ControlCenter (CDC)/zoonotic diseases section between 2015-2019. Results: Out of 206 suspected cases, only 17 were diagnosed as CCHF with a total fatality ratio of 52%, 25%, and 80% in 2015and 2018 respectively. However, no mortality was reported during 2016, 2017, and 2019. The mean age of the patients was 33years± 18 SD, in males mainly (76%). Moreover, the risk groups were 29 %, 23 %, 18 % 12 %, and 6 % for butchers, animaldealers, gainers, both housewives and students and children respectively. Conclusion: Strict precautions and precise surveillance should be implemented to control the disease and protect the communityby improving the diagnosis and treatment of CCHF. The authors recommend another future study to detect the genotypingand sequencing of CCHFV in Iraq. Keywords: Crimean–Congo hemorrhagic fever; Iraq; tick.
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