拉丁美洲某国使用玻璃体内贝伐单抗治疗 I 型早产儿视网膜病变的经验

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引用次数: 0

摘要

在 I 型早产儿视网膜病变(ROP)中,玻璃体内贝伐单抗(IVB)是一种内皮生长因子(VEGF)抑制剂,尽管尚未获得监管机构的批准,但它的使用已变得非常普遍。然而,与其他抗血管内皮生长因子疗法(ranibizumab 或 aflibercept)相比,IVB 在阻止疾病进展方面已显示出积极的效果,而且成本更低。在本报告中,我们介绍了对 102 名哥伦比亚 I 型视网膜病变患儿进行 IVB 治疗的经验,成功率为 98%(100 例)。并发症发生率为 3.9%(4 例)。最后,我们得出结论:单剂量 IVB 是治疗 I 型视网膜病变的有效疗法,并发症和再治疗的风险较低。
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Experiencia con el uso de bevacizumab intravítreo en el manejo de la retinopatía del prematuro tipo I en un país latinoamericano

In retinopathy of prematurity (ROP) type I, the use of intravitreal bevacizumab (IVB), which is an inhibitor of endothelial growth factor (VEGF), has become popular despite not being a therapy approved by regulatory agencies. However, IVB has shown positive effects in halting disease progression at lower costs compared to other anti-VEGF therapies (ranibizumab or aflibercept). In this report, we present the experience during the treatment with IVB of 102 Colombian children with ROP type I, with a success rate of 98% (100). Complications occurred in 3.9% (4). Finally, we conclude that a single dose of IVB is an effective therapy for the management of ROP type I, with a lower risk of complications and retreatment.

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来源期刊
CiteScore
1.20
自引率
0.00%
发文量
109
审稿时长
78 days
期刊介绍: La revista Archivos de la Sociedad Española de Oftalmología, editada mensualmente por la propia Sociedad, tiene como objetivo publicar trabajos de investigación básica y clínica como artículos originales; casos clínicos, innovaciones técnicas y correlaciones clinicopatológicas en forma de comunicaciones cortas; editoriales; revisiones; cartas al editor; comentarios de libros; información de eventos; noticias personales y anuncios comerciales, así como trabajos de temas históricos y motivos inconográficos relacionados con la Oftalmología. El título abreviado es Arch Soc Esp Oftalmol, y debe ser utilizado en bibliografías, notas a pie de página y referencias bibliográficas.
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