{"title":"通过 MMP 分析为分子设计提供启示","authors":"Matthew L. Landry","doi":"10.1016/j.trechm.2024.04.001","DOIUrl":null,"url":null,"abstract":"<p>Matched molecular pair (MMP) analysis is a powerful technique to assess the impact of a structural change on the collective properties of a molecule. This is particularly valuable in medicinal chemistry and drug development, which require the balancing of a range of molecular properties simultaneously.</p>","PeriodicalId":48544,"journal":{"name":"Trends in Chemistry","volume":"2 1","pages":""},"PeriodicalIF":14.0000,"publicationDate":"2024-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Deriving insights for molecular design with MMP analysis\",\"authors\":\"Matthew L. Landry\",\"doi\":\"10.1016/j.trechm.2024.04.001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Matched molecular pair (MMP) analysis is a powerful technique to assess the impact of a structural change on the collective properties of a molecule. This is particularly valuable in medicinal chemistry and drug development, which require the balancing of a range of molecular properties simultaneously.</p>\",\"PeriodicalId\":48544,\"journal\":{\"name\":\"Trends in Chemistry\",\"volume\":\"2 1\",\"pages\":\"\"},\"PeriodicalIF\":14.0000,\"publicationDate\":\"2024-04-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Trends in Chemistry\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.1016/j.trechm.2024.04.001\",\"RegionNum\":2,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Trends in Chemistry","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1016/j.trechm.2024.04.001","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
Deriving insights for molecular design with MMP analysis
Matched molecular pair (MMP) analysis is a powerful technique to assess the impact of a structural change on the collective properties of a molecule. This is particularly valuable in medicinal chemistry and drug development, which require the balancing of a range of molecular properties simultaneously.
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Trends in Chemistry serves as a new global platform for discussing significant and transformative concepts across all areas of chemistry. It recognizes that breakthroughs in chemistry hold the key to addressing major global challenges. The journal offers readable, multidisciplinary articles, including reviews, opinions, and short pieces, designed to keep both students and leading scientists updated on pressing issues in the field.
Covering analytical, inorganic, organic, physical, and theoretical chemistry, the journal highlights major themes such as biochemistry, catalysis, environmental chemistry, materials, medicine, polymers, and supramolecular chemistry. It also welcomes articles on chemical education, health and safety, policy and public relations, and ethics and law.
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