探索噬菌体质粒在基因转移中的作用

IF 13.6 2区生物学 Q1 GENETICS & HEREDITY Trends in Genetics Pub Date : 2024-04-29 DOI:10.1016/j.tig.2024.04.011

Agnieszka K. Szczepankowska, Małgorzata Łobocka

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引用次数: 0

摘要

噬菌体和质粒推动了细菌中的水平基因转移（HGT）。噬菌体-质粒（P-Ps）是质粒和噬菌体的杂交种。Pfeifer 和 Rocha 最近证明，P-Ps 可作为这两类元素之间基因交换的中间体，确定了优先转移基因的类别，并重建了涉及噬菌体 P1 类 P-Ps 的基因流。

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Exploring the role of phage plasmids in gene transfers

Bacteriophages and plasmids drive horizontal gene transfer (HGT) in bacteria. Phage-plasmids (P-Ps) are hybrids of plasmid and phages. Pfeifer and Rocha recently demonstrated that P-Ps can serve as intermediates in gene exchanges between these two types of elements, identified categories of preferentially transferred genes, and reconstructed gene flows involving phage P1-like P-Ps.

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来源期刊

Trends in Genetics 生物-遗传学

CiteScore

20.90

自引率

0.90%

发文量

160

审稿时长

6-12 weeks

期刊介绍： Launched in 1985, Trends in Genetics swiftly established itself as a "must-read" for geneticists, offering concise, accessible articles covering a spectrum of topics from developmental biology to evolution. This reputation endures, making TiG a cherished resource in the genetic research community. While evolving with the field, the journal now embraces new areas like genomics, epigenetics, and computational genetics, alongside its continued coverage of traditional subjects such as transcriptional regulation, population genetics, and chromosome biology. Despite expanding its scope, the core objective of TiG remains steadfast: to furnish researchers and students with high-quality, innovative reviews, commentaries, and discussions, fostering an appreciation for advances in genetic research. Each issue of TiG presents lively and up-to-date Reviews and Opinions, alongside shorter articles like Science & Society and Spotlight pieces. Invited from leading researchers, Reviews objectively chronicle recent developments, Opinions provide a forum for debate and hypothesis, and shorter articles explore the intersection of genetics with science and policy, as well as emerging ideas in the field. All articles undergo rigorous peer-review.

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