重庆市未接种疫苗献血者 SARS-CoV-2 抗体的筛查与分析

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-05-03 DOI:10.1017/dmp.2023.232
Yulin Jiang, Lijuan Huang, Hongmei Liao, Chenghui Luo, Chunhong Zhang, Wei Mao
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引用次数: 0

摘要

目的调查重庆市未接种疫苗的自愿献血者中严重急性呼吸系统综合征冠状病毒 2(SARS-CoV-2)抗体的感染率,为疫情监测提供证据。研究方法收集重庆地区2021年1月5日至1月20日10208名无偿献血者,采用化学发光法检测SARS-CoV-2免疫球蛋白(Ig)G和IgM抗体,分析不同性别、年龄、ABO血型和不同危险地区抗体阳性率的差异。结果显示在 10208 名献血者中,发现 10 人 SARS-COV-2 IgG 抗体阳性,SARS-CoV-2 IgG 阳性率为 0.10%;29 人 SARS-CoV-2 IgM 抗体阳性,SARS-CoV-2 IgM 阳性率为 0.28%。不同性别、年龄和ABO血型之间的抗体阳性率无统计学差异,但与各城市2019年冠状病毒病(COVID-19)确诊病例数有关。结论重庆的SARS-CoV-2血清阳性率较低,且与COVID-19确诊病例数相关。
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Screening and Analysis of SARS-CoV-2 Antibody Among Unvaccinated Blood Donors in Chongqing, China
Objective: To investigate the rate of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibody among unvaccinated voluntary blood donors in Chongqing, and to provide evidence for epidemic surveillance. Methods: A total of 10,208 voluntary blood donors from January 5 to January 20, 2021, in the Chongqing area were collected, and the SARS-CoV-2 immunoglobulin (Ig) G and IgM antibodies were detected by chemiluminescence, and the differences of antibody-positive rate in different gender, age, ABO blood group, and different risk areas were analyzed. Results: Among 10208 blood donors, 10 were found to be positive for SARS-COV-2 IgG antibody, giving a positivity rate of SARS-COV-2 IgG at 0.10%, and 29 were positive for SARS-CoV-2 IgM antibody, with a positivity rate of SARS-CoV-2 IgM at 0.28%. There was no statistical difference in the positive rate of antibody among different genders, ages, and ABO blood types, but it was related to the number of confirmed coronavirus disease 2019 (COVID-19) cases in each city. Conclusions: The SARS-CoV-2 seroprevalence rate in Chongqing was low and correlated with the number of confirmed COVID-19 cases.
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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