致命的页肾误诊--病例报告。

IF 1.5 4区 医学 Q2 MEDICINE, LEGAL Forensic Science, Medicine and Pathology Pub Date : 2024-12-01 Epub Date: 2024-04-13 DOI:10.1007/s12024-024-00807-6
Gayan Kumarasinghe, Murugupillai Sivasubramanium, Kasun Bandara Ekanayake, Dhanushka Rambukwella, Bandarage Sanjaya
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引用次数: 0

摘要

肾脏受压是指肾动脉和肾实质受到外部压迫,从而导致缺血和肾素-血管紧张素-醛固酮轴的激活。一名 42 岁女性患者患有多毛症、高血压和糖尿病,被诊断为右侧肾上腺肿块,并接受了腹腔镜肾上腺切除术。她的高血压在术后恶化,接受了药物治疗。随后,她在术后第五天出现右侧腹痛,第二天突然死亡。尸体解剖显示她面色苍白,外观呈库欣样。手术疤痕健康。腹部内部检查显示腹腔积血 500 毫升,右肾周围有一个 1000 毫升的巨大囊下血肿,压迫右肾动脉。肾脏颜色苍白,右肾柔软易碎。右肾皮质表面显示有一个可能的手术穿刺点,上覆血栓,下腔静脉挫伤。其他器官颜色苍白,但看起来正常。组织学检查显示右肾皮质弥漫性坏死,肺部有成人呼吸窘迫综合征的特征。腹腔镜肾上腺切除术治疗右肾上腺肿瘤后的失血性休克被宣布为死亡原因,佩奇肾脏的发育也是原因之一。包括腹腔镜腹部手术在内的多种病因的创伤都可能导致佩奇肾。它表现为侧腹疼痛、高血压和肾肿块。由于术后失血通常表现为低血压,因此高血压可能会误导临床医生。一旦确诊,可通过手术引流和服用降压药来控制病情。
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A fatal misdiagnosis of page kidney - case report.

Page kidney is a condition where external compression of the renal artery and renal parenchyma leads to subsequent ischaemia and activation of renin-angiotensin-aldosterone axis. A 42-year-old female with hirsutism, hypertension and diabetes was diagnosed with a right adrenal mass and underwent laparoscopic adrenalectomy. Her hypertension worsened postoperatively and was managed medically. Subsequently she developed a right flank pain on the fifth postoperative day and died suddenly the next day. Autopsy revealed a pale body with cushingoid appearance. Surgical scars were healthy. Internal examination of the abdomen revealed a haemoperitoneum of 500 ml together with a large subcapsular haematoma measuring 1000 ml surrounding the right kidney, compressing the right renal artery. Kidneys were pale and the right kidney was soft and friable. Cortical surface of the right kidney demonstrated a possible surgical puncture site with an overlying thrombus together with a contused inferior vena cava. Other organs were pale but appeared otherwise normal. Histology revealed diffuse cortical necrosis of right kidney and features of adult respiratory distress syndrome in the lungs. Haemorrhagic shock following laparoscopic adrenalectomy for right adrenal tumor was declared as the cause of death, contributed by the development of the Page kidney. Trauma of several aetiologies including laparoscopic abdominal surgery may contribute to Page kidney. It presents with flank pain, hypertension and renal mass. Since postoperative blood loss usually manifests as hypotension, resulting hypertension may mislead the attending clinicians. Once diagnosed, it can be managed with surgical drainage and antihypertensives.

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来源期刊
Forensic Science, Medicine and Pathology
Forensic Science, Medicine and Pathology MEDICINE, LEGAL-PATHOLOGY
CiteScore
3.90
自引率
5.60%
发文量
114
审稿时长
6-12 weeks
期刊介绍: Forensic Science, Medicine and Pathology encompasses all aspects of modern day forensics, equally applying to children or adults, either living or the deceased. This includes forensic science, medicine, nursing, and pathology, as well as toxicology, human identification, mass disasters/mass war graves, profiling, imaging, policing, wound assessment, sexual assault, anthropology, archeology, forensic search, entomology, botany, biology, veterinary pathology, and DNA. Forensic Science, Medicine, and Pathology presents a balance of forensic research and reviews from around the world to reflect modern advances through peer-reviewed papers, short communications, meeting proceedings and case reports.
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