患者的用药观念对社区老年人的影响及其与次优用药的关系:定量研究的系统回顾。

IF 2.6 4区 医学 Q2 PHARMACOLOGY & PHARMACY International Journal of Clinical Pharmacy Pub Date : 2024-08-01 Epub Date: 2024-05-05 DOI:10.1007/s11096-024-01727-9
Eman Rafhi, Malath Al-Juhaishi, Ieva Stupans, Julie E Stevens, Joon Soo Park, Kate N Wang
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引用次数: 0

摘要

背景:老年人的用药量在不断增加,因此,要达到最佳治疗效果,就必须降低次优用药的风险。研究表明,个人信念和对药物的信念等因素可能与不依从性和不适当用药有关。目的:系统回顾并确定有关药物信念的影响以及与老年人次优用药之间关系的定量研究:方法: 在 PubMed、EMBASE、CINAHL 和 PsycINFO 上检索定量研究(开始至 2023 年 3 月):(1) 暴露:参与者的信念(个人、文化和用药相关);(2) 结果:多重用药、潜在用药不当或不依从;(3) 参与者:65 岁或以上居住在社区的成年人。研究选择、数据提取和质量评估(乔安娜-布里格斯研究所关键评估清单)由两名调查人员独立完成。数据以叙述性综述的形式进行合并,并在研究结果摘要表中列出:结果:共纳入 19 篇文章:结果:共纳入 19 篇文章:15 篇横断面研究和 4 篇队列研究。收录论文的结果如下:依从性(18 篇)和潜在用药不当(1 篇)。十项研究发现,对药物必要性的更强信念和/或更少的担忧会导致更好的依从性,有一篇论文与这些研究结果相矛盾。三项研究未发现依从性与信念之间存在关联。一项研究证实,不必要的药物使用与缺乏对 "强大的他人"(如医生)的信念有关:有必要开展进一步调查,以便(1)确定必要性或关注信念在促进坚持用药方面的重要性,以及(2)研究信念对多药疗法和不当用药的影响。
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The influence of patients' beliefs about medicines and the relationship with suboptimal medicine use in community-dwelling older adults: a systematic review of quantitative studies.

Background: Medication use in older adults is increasing, therefore, reducing the risk of suboptimal medicine use is imperative in achieving optimal therapeutic outcomes. Research suggests that factors such as personal beliefs and beliefs about medicines may be associated with non-adherence and inappropriate medicine use.

Aim: To systematically review and identify quantitative research on the influence of beliefs about medicines and the relationship with suboptimal medicine use in older adults.

Method: Searches were conducted on PubMed, EMBASE, CINAHL, and PsycINFO for quantitative studies (inception to March 2023).

Inclusion criteria: (1) exposure: participants' beliefs (personal, cultural, and medication-related), (2) outcomes: polypharmacy, potentially inappropriate medicines use, or non-adherence, and (3) participants: community-dwelling adults 65 years or above. Study selection, data extraction and quality appraisal (Joanna Briggs Institute critical appraisal checklist) were completed independently by two investigators. Data were combined in a narrative synthesis and presented in a summary of findings table.

Results: Nineteen articles were included: 15 cross-sectional and four cohort studies. Outcomes of included papers were as follows; adherence (n = 18) and potentially inappropriate medicine use (n = 1). Ten studies found stronger beliefs in the necessity of medicines and/or fewer concerns led to better adherence, with one paper contradicting these findings. Three studies did not find associations between adherence and beliefs. One study confirmed an association between unnecessary drug use and a lack of belief in a "powerful other" (e.g. doctor).

Conclusion: Further investigation is necessary to (1) ascertain the importance of necessity or concern beliefs in fostering adherence and, (2) examine the influence of beliefs on polypharmacy and inappropriate medicine use.

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来源期刊
CiteScore
4.10
自引率
8.30%
发文量
131
审稿时长
4-8 weeks
期刊介绍: The International Journal of Clinical Pharmacy (IJCP) offers a platform for articles on research in Clinical Pharmacy, Pharmaceutical Care and related practice-oriented subjects in the pharmaceutical sciences. IJCP is a bi-monthly, international, peer-reviewed journal that publishes original research data, new ideas and discussions on pharmacotherapy and outcome research, clinical pharmacy, pharmacoepidemiology, pharmacoeconomics, the clinical use of medicines, medical devices and laboratory tests, information on medicines and medical devices information, pharmacy services research, medication management, other clinical aspects of pharmacy. IJCP publishes original Research articles, Review articles , Short research reports, Commentaries, book reviews, and Letters to the Editor. International Journal of Clinical Pharmacy is affiliated with the European Society of Clinical Pharmacy (ESCP). ESCP promotes practice and research in Clinical Pharmacy, especially in Europe. The general aim of the society is to advance education, practice and research in Clinical Pharmacy . Until 2010 the journal was called Pharmacy World & Science.
期刊最新文献
Association of polypharmacy with clinical outcomes and healthcare utilization in older adults with cardiometabolic diseases: a retrospective cohort study. Correction: Development and validation of a Medication Adherence Universal Questionnaire: the MAUQ. Global trends in pharmacovigilance-related events: a 30-year analysis from the 2019 global burden of disease study. Medication errors in emergency departments: a systematic review and meta-analysis of prevalence and severity. A randomised, crossover trial exploring the patient perspective and effectiveness of biosimilar adalimumab transition: IBD reference and biosimilar adalimumab cross over study (iBaSS).
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