SARS-CoV-2 感染引起的口腔溃疡:病例报告。

IF 0.7 Q3 MEDICINE, GENERAL & INTERNAL AME Case Reports Pub Date : 2024-03-11 eCollection Date: 2024-01-01 DOI:10.21037/acr-23-158
Lucie Rapp, Thomas Gémar, Marie-Hélène Lacoste-Ferré
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摘要

背景:2019年底出现的严重急性呼吸综合征冠状病毒2(SARS-CoV-2)引起了全球大流行。冠状病毒病 2019(COVID-19)的口腔和皮肤病表现,如口角炎、口疮样病变、溃疡、舌下垂、坏死性牙龈炎以及味觉障碍,包括味觉丧失和唾液腺感染等,均有报道。本研究旨在描述一例感染 COVID-19 后出现口腔溃疡的病例:本病例是一名 95 岁的男性患者,在法国图卢兹 Minimes 老年病诊所的后续护理和康复科住院治疗。通过反转录聚合酶链式反应(RT-PCR)检测,该患者感染了 COVID-19,导致其全身健康状况发生变化。入院六天后,患者主诉口腔有强烈的灼烧感,尤其是舌头和嘴唇粘膜。口腔内检查发现,舌头外侧边缘和下唇粘膜有疼痛的糜烂区域。为减轻灼烧感,医生建议采用全身镇痛剂(硫酸吗啡)、碳酸氢钠漱口水、利多卡因口腔麻醉剂和愈合凝胶以及舒适饮食等治疗方法。13 天后,患者的病情逐渐好转:结论:在有 COVID-19 感染史的患者中观察到了多种多样的口腔表现。这些口腔溃疡严重影响患者的生活质量,导致剧烈疼痛、压力和进食困难,并对营养状况产生影响,尤其是对老年人而言。我们的病例强调了口腔检查的重要性以及牙医在治疗 SARS-CoV-2 患者中的作用。
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Oral ulcer in SARS-CoV-2 infection: a case report.

Background: The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) at the end of 2019 caused the global pandemic. Oral and dermatological manifestations of coronavirus disease 2019 (COVID-19) such as xerostomia, aphthous-like lesions, ulcers, tongue depapillation, necrotizing gingivitis, and taste disorders, including the loss of taste and salivary gland infections are being reported. This study aims to describe a case of oral ulcers following COVID-19 infection.

Case description: We present the case of a 95-year-old male patient hospitalized in follow-up care and rehabilitation unit, of Minimes Geriatric Clinic, Toulouse, France. He had an alteration in his general health in the context of COVID-19 infection detected by reverse transcription polymerase chain reaction (RT-PCR). Six days after the admission, the patient complained of a strong burning sensation of the mouth, especially on the tongue and the lips' mucosa. Intraoral examination revealed painful erosive areas on the lateral edges of the tongue and the mucous side of the lower lip. The proposed treatment to reduce the burning sensation was based on general analgesics (morphine sulfate), mouthwash with sodium bicarbonate, the application of a lidocaine-based oral anesthetic and healing gel and a comfort-oriented diet. Thirteen days later, the patient reported a gradual improvement.

Conclusions: A diverse range of oral manifestations has been observed in patients with a history of COVID-19 infection. These oral ulcers significantly impact the quality of life of the individual, causing intense pain, stress, and difficulties in eating, with repercussions on nutritional status, especially in older individuals. Our case underscores the importance of oral examinations and the role of dentists in the management of patients with SARS-CoV-2.

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