癌症前兆综合征及其在头颈部的检测。

IF 2.5 3区 医学 Q2 HEMATOLOGY Hematology-Oncology Clinics of North America Pub Date : 2024-05-04 DOI:10.1016/j.hoc.2024.04.001
Alessandro Villa DDS, PhD, MPH , William N. William Jr. MD , Glenn J. Hanna MD
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引用次数: 0

摘要

本文探讨了口腔癌前兆综合征的多面性。先天性角化障碍和范可尼贫血等遗传性疾病会增加罹患恶性肿瘤的风险。口腔潜在恶性疾病,特别是白斑病,作为受遗传和免疫学影响的前体疾病进行了讨论。分子研究深入探讨了基因突变、等位基因失衡和免疫调节在癌前病变进展中的关键作用,并提出了潜在的治疗目标。文章探讨了白斑病治疗策略的争议领域,包括手术切除、化学预防和免疫调节,同时强调了开发有效的循证预防方法所面临的持续挑战。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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Cancer Precursor Syndromes and Their Detection in the Head and Neck
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来源期刊
CiteScore
4.10
自引率
0.00%
发文量
86
审稿时长
6-12 weeks
期刊介绍: Hematology/Oncology Clinics updates you on the latest trends in patient management, keeps you up to date on the newest advances, and provides a sound basis for choosing treatment options. Under the direction of an experienced guest editor, each issue focuses on a single topic in hematology and oncology, including hemostasis and thrombosis, molecular and cellular basis of hematology, coagulation disorders, and cancers—bone, gastrointestinal, head and neck, lymphomas, neuroendocrine, breast, renal cell, melanoma, and more.
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