{"title":"代谢健康的肥胖与健康风险--荟萃分析综述。","authors":"Erika Čermáková, Martin Forejt","doi":"10.21101/cejph.a7806","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>This article briefly summarizes the results of existing research on metabolically healthy obesity in the context of health risks.</p><p><strong>Methods: </strong>The PubMed database was searched for relevant meta-analyses addressing metabolically healthy obesity in the context of health risks.</p><p><strong>Results: </strong>We included a total of 17 relevant meta-analyses in this review. The results of the studied meta-analyses showed that metabolically healthy obesity may be only a transient condition associated with an increased risk of developing metabolic abnormalities in the future. People with obesity without metabolic abnormalities have an increased risk of type 2 diabetes, cardiovascular disease, cancer, chronic kidney disease, and depressive syndrome. In addition, all people with obesity are at risk of pathogenesis resulting from the mechanical stress caused by presence of abnormal adipose tissue, such as sleep apnoea syndrome or skin problems.</p><p><strong>Conclusion: </strong>Based on the results of meta-analyses, we recommend motivating all obese patients to change their lifestyle regardless of the presence of metabolic defects.</p>","PeriodicalId":9823,"journal":{"name":"Central European journal of public health","volume":null,"pages":null},"PeriodicalIF":1.1000,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Metabolically healthy obesity and health risks - a review of meta-analyses.\",\"authors\":\"Erika Čermáková, Martin Forejt\",\"doi\":\"10.21101/cejph.a7806\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>This article briefly summarizes the results of existing research on metabolically healthy obesity in the context of health risks.</p><p><strong>Methods: </strong>The PubMed database was searched for relevant meta-analyses addressing metabolically healthy obesity in the context of health risks.</p><p><strong>Results: </strong>We included a total of 17 relevant meta-analyses in this review. The results of the studied meta-analyses showed that metabolically healthy obesity may be only a transient condition associated with an increased risk of developing metabolic abnormalities in the future. People with obesity without metabolic abnormalities have an increased risk of type 2 diabetes, cardiovascular disease, cancer, chronic kidney disease, and depressive syndrome. In addition, all people with obesity are at risk of pathogenesis resulting from the mechanical stress caused by presence of abnormal adipose tissue, such as sleep apnoea syndrome or skin problems.</p><p><strong>Conclusion: </strong>Based on the results of meta-analyses, we recommend motivating all obese patients to change their lifestyle regardless of the presence of metabolic defects.</p>\",\"PeriodicalId\":9823,\"journal\":{\"name\":\"Central European journal of public health\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.1000,\"publicationDate\":\"2024-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Central European journal of public health\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.21101/cejph.a7806\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Central European journal of public health","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.21101/cejph.a7806","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
Metabolically healthy obesity and health risks - a review of meta-analyses.
Objective: This article briefly summarizes the results of existing research on metabolically healthy obesity in the context of health risks.
Methods: The PubMed database was searched for relevant meta-analyses addressing metabolically healthy obesity in the context of health risks.
Results: We included a total of 17 relevant meta-analyses in this review. The results of the studied meta-analyses showed that metabolically healthy obesity may be only a transient condition associated with an increased risk of developing metabolic abnormalities in the future. People with obesity without metabolic abnormalities have an increased risk of type 2 diabetes, cardiovascular disease, cancer, chronic kidney disease, and depressive syndrome. In addition, all people with obesity are at risk of pathogenesis resulting from the mechanical stress caused by presence of abnormal adipose tissue, such as sleep apnoea syndrome or skin problems.
Conclusion: Based on the results of meta-analyses, we recommend motivating all obese patients to change their lifestyle regardless of the presence of metabolic defects.
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The Journal publishes original articles on disease prevention and health protection, environmental impacts on health, the role of nutrition in health promotion, results of population health studies and critiques of specific health issues including intervention measures such as vaccination and its effectiveness. The review articles are targeted at providing up-to-date information in the sphere of public health. The Journal is geographically targeted at the European region but will accept specialised articles from foreign sources that contribute to public health issues also applicable to the European cultural milieu.
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