用阿立哌唑治疗阿斯伯格综合症患者,患者出现幻想和身体摇晃的症状--病例报告。

IF 0.9 4区 医学 Q4 PSYCHIATRY Psychiatria polska Pub Date : 2023-12-31 DOI:10.12740/PP/152316
Maciej Dul, Krzysztof Walczewski
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引用次数: 0

摘要

在这篇文章中,我们介绍了一名成年患者的病例,他的主要问题是幻想和摇摆发作,每天持续长达 12 个小时,完全妨碍了学业发展。该患者的障碍性质与沉浸在幻想中有关,而不是强迫症的典型强迫症。患者曾接受过 SSRI 类药物、神经安定剂(不含阿立哌唑)和哌醋甲酯的治疗。只有哌醋甲酯有所改善,但却让患者感到 "思维僵硬"。患者因自杀未遂而住院,但后来发现,他只是自残,并没有自杀的意图。住院期间进行了鉴别诊断,诊断结果为阿斯伯格综合症,并伴有沉浸于自己的幻想世界和刻板行为。患者接受了阿立哌唑治疗,剂量为 15 毫克/天,三周后,健康状况明显改善,包括发作时间从几小时缩短到几十秒。患者对药物的耐受性良好。患者出院后继续在校学习。在这篇文章中,我们介绍了在类似病例中取得类似惊人效果的单个病例报告。我们还描述了这种药物反应的可能生理解释。
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Patient with Asperger's Syndrome, with episodes of fantasizing and rocking of body, treated with aripiprazole - a case report.

In this article, we present the case of an adult patient, whose main problem is episodes of fantasizing and rocking lasting up to 12 hours a day and completely preventing school development. The nature of the disorder in the patient is related to the sinking into fantasies, and not typical obsessions as in OCD. The patient was previously treated with drugs from the SSRI group, neuroleptics (without aripiprazole) and methylphenidate. Only methylphenidate showed some improvement; however, it made the patient feel ‟stiff in thinking". The patient was hospitalized because of a suicide attempt, which, as it later turned out, was self-harm with no intention of killing himself. During hospitalization, a differential diagnosis was performed and the diagnosis of Asperger's syndrome was made, which was accompanied by immersion in the world of one's fantasies and stereotypical behavior. The patient was administered aripiprazole at a dose of 15 mg/d and after three weeks, a significant improvement in health was achieved, including a reduction in the duration of episodes from several hours to several dozen seconds. The drug is well tolerated by the patient. The patient was discharged from the hospital and continues his school education. In the article, we present single case reports in which similar spectacular results were achieved in similar cases. We also describe a possible physiological explanation for this response to this drug.

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来源期刊
Psychiatria polska
Psychiatria polska 医学-精神病学
CiteScore
2.30
自引率
23.50%
发文量
92
审稿时长
6-12 weeks
期刊介绍: Information not localized
期刊最新文献
Study directions and development of cognitive theory of depression. Prevalence and determinants of psychotropic medication use in Poland. Efficacy and safety of aripiprazole in the treatment of delirium. An outline of savant syndrome. Use of the opioid receptor antagonist - naltrexone in the treatment of non-suicidal self-injury.
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