Lena Marie Wilms, Kai Jannusch, Daniel Weiss, Nilcolas Steinfort, Farid Ziayee, Gerald Antoch, Peter Minko
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引用次数: 0
摘要
骨关节炎（OA）是一种慢性退行性疾病，严重影响患者的生活质量和社会经济。传统的治疗方法，包括药物和手术干预，往往效果有限。我们对 OA 背后病理机制的进一步了解表明，病理血管生成参与其中。经动脉微栓塞术（TAME）是一种微创放射手术，可能是一种创新的治疗方法。本综述旨在整合目前有关经动脉微栓塞术（TAME）的知识和经验，将其作为缓解与 OA 相关的慢性关节疼痛的一种治疗方式。它探讨了 TAME 的作用，重点关注其适应症、患者选择、临床结果和未来展望。文章系统地探讨了潜在的并发症和相关风险，并提出了降低风险和有效管理的策略。TAME是一种很有前景的治疗方法，可减轻关节疾病的负担，大大提高患者的生活质量。临床结果表明，TAME 在减轻 OA 相关慢性关节疼痛患者的疼痛和改善其功能方面具有良好的疗效和安全性。越来越多的证据表明，TAME 对多种关节相关病症都有治疗效果和适用性，它为这些病症的治疗方法提供了宝贵的补充。- TAME 是一种治疗与 OA 相关的慢性关节疼痛的创新疗法。- TAME是一种具有技术挑战性的微创介入疗法，需要高水平的专业知识。- 了解TAME的挑战和并发症可以降低风险并提高手术效果。- Wilms LM、Jannusch K、Weiss D 等人.经动脉微栓塞治疗骨关节炎难治性慢性关节疼痛.......Fortschr Röntgenstr 2024; DOI 10.1055/a-2288-5743。
Transarterial microembolization for the management of refractory chronic joint pain in osteoarthritis.
Osteoarthritis (OA) is a chronic degenerative disease significantly impacting both patient quality of life and socioeconomics. Traditional treatment options, including pharmacological and surgical interventions, are often limited. Advancements in our understanding of the pathological mechanisms behind OA indicate the involvement of pathological angiogenesis. Transarterial microembolization (TAME), a minimally invasive radiological procedure, may present an innovative therapeutic approach. This review aims to consolidate current knowledge and experiences regarding TAME as a therapeutic modality for alleviating chronic joint pain associated with OA. It explores the role of TAME, focusing on its indications, patient selection, clinical outcomes, and future perspectives. Potential complications and associated risks are systematically addressed, alongside proposed strategies for risk mitigation and effective management.The presented patient cases originate from our institution, supplemented by a thorough review of relevant literature retrieved from PubMed.TAME represents a promising therapeutic approach, providing relief from the burden of joint diseases and substantially enhancing patient quality of life. Clinical outcomes emphasize the efficacy and safety of TAME in mitigating pain and improving functional capabilities in patients with chronic joint pain associated with OA. With mounting evidence of its therapeutic benefits and applicability to numerous joint-related pathologies, TAME offers a valuable addition to the arsenal of treatments for these conditions. · TAME is an innovative therapy for treating chronic joint pain related to OA.. · TAME is a technically challenging minimally invasive intervention requiring a high level of expertise.. · Understanding the challenges and complications of TAME can reduce risk and enhance procedural outcomes.. · Wilms LM, Jannusch K, Weiss D et al. Transarterial microembolization for the management of refractory chronic joint pain in osteoarthritis. Fortschr Röntgenstr 2024; DOI 10.1055/a-2288-5743.
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