应用高分辨率太赫兹光谱研究典型耳鼻喉病变生物膜

IF 0.8 4区 地球科学 Q4 ENGINEERING, ELECTRICAL & ELECTRONIC Radiophysics and Quantum Electronics Pub Date : 2024-05-13 DOI:10.1007/s11141-024-10320-z
V. L. Vaks, A. A. Aizenshtadt, V. A. Anfertev, E. G. Domracheva, M. B. Chernyaeva, P. P. Mokeeva, D. V. Kryazhev
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引用次数: 0

摘要

生物膜是细菌联合存在的主要类型,具有空间和代谢结构,在人体粘膜上形成。研究慢性腺扁桃体炎的主要病原体及其形成生物膜的能力,以及组织代谢物的鉴定和证实病原体影响的比较分析,是利用高分辨率太赫兹气体光谱法进行的。研究了金黄色葡萄球菌、化脓性链球菌、肺炎克雷伯氏菌和大肠杆菌形成的生物膜,以揭示其热分解产物,并确定微生物的特征集合。不同微生物的生物膜热分解产物集显示了其成分差异,可用于创建细菌代谢图谱和医学诊断方法。
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Application of High-Resolution Terahertz Spectroscopy for Studying Biofilms Typical of ENT Pathologies

A biofilm as the main type of existence of bacterial associations, which has its spatial and metabolic structure, is formed on the mucosa in a human body. The study of the main pathobionts and their abilities for biofilm formation at chronic adenotonsillitis, with the identification of tissue metabolites and a comparative analysis confirming the effect of the pathogen, is carried out using the methods of high-resolution terahertz gas spectroscopy. The biofilms formed by Staphylococcus aureus, Streptococcus pyogenes, Klebsiella pneumoniae, and Enterobacter coli are studied to reveal products of their thermal decomposition and identify the set which is characteristic of microorganisms. The sets of thermal-decomposition products of biofilms for different microorganisms demonstrate the composition difference, which can be used to create metabolic profiles of bacteria and the medical diagnostics methods.

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来源期刊
Radiophysics and Quantum Electronics
Radiophysics and Quantum Electronics ENGINEERING, ELECTRICAL & ELECTRONIC-PHYSICS, APPLIED
CiteScore
1.10
自引率
12.50%
发文量
60
审稿时长
6-12 weeks
期刊介绍: Radiophysics and Quantum Electronics contains the most recent and best Russian research on topics such as: Radio astronomy; Plasma astrophysics; Ionospheric, atmospheric and oceanic physics; Radiowave propagation; Quantum radiophysics; Pphysics of oscillations and waves; Physics of plasmas; Statistical radiophysics; Electrodynamics; Vacuum and plasma electronics; Acoustics; Solid-state electronics. Radiophysics and Quantum Electronics is a translation of the Russian journal Izvestiya VUZ. Radiofizika, published by the Radiophysical Research Institute and N.I. Lobachevsky State University at Nizhnii Novgorod, Russia. The Russian volume-year is published in English beginning in April. All articles are peer-reviewed.
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