非阻塞性冠状动脉疾病和冠状动脉微血管功能障碍患者强化体外反搏与心脏康复的随机对照研究 临床持续效果

IF 1.2 4区 医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS International heart journal Pub Date : 2024-05-15 DOI:10.1536/ihj.23-454
Yuanzhuo Zhang, Xiaoyan Yin, Lei Ren
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引用次数: 0

摘要

增强体外反搏(EECP)或心脏康复(CR)治疗对冠心病患者有益,本文拟探讨EECP联合CR治疗非梗阻性冠心病(NOCAD)和冠状动脉微循环障碍(CMD)患者的可行性。以2021年1月-2022年6月我院收治的NOCAD患者为研究对象,行心脏磁共振(CMR)、心肌灌注储备(MPR)<2.0冠状动脉微循环障碍(CMD,80例)。随机指标法 80 例 CMD 患者分为两组,每组 40 例。常规治疗组:常规药物和 CR 治疗。EECP 治疗组:在标准治疗组的基础上,采用 EECP 治疗。比较两组治疗前后疗效心功能指标、内皮功能指标、心血管不良事件等。EECP治疗后,治疗组有效率高于常规治疗组(P< 0.05)。EECP组疗效、左室射血分数、血浆NO和血管内皮生长因子水平高于常规组,心血管不良事件发生率低于常规组,差异有统计学意义(P<0.05)。EECP联合心脏康复治疗CMD症状患者效果更好,安全性更高,为CMD患者的治疗提供了参考。
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A Randomized Controlled Study of Enhanced External Counterpulsation with Cardiac Rehabilitation in Patients with Nonobstructive Coronary Artery Disease and Coronary Microvascular Dysfunction Clinical Durative Effect

Treatment with enhanced external counterpulsation (EECP) or cardiac rehabilitation (CR) benefits patients with coronary heart disease; this paper intends to explore the feasibility of EECP combined with CR in patients with nonobstructive coronary heart disease (NOCAD) and coronary microcirculation disorders (CMD).

In January 2021-2022 month June our income NOCAD patients as the research object, the line of cardiac magnetic resonance (CMR), myocardial perfusion reserve (MPR) < 2.0 coronary microcirculation disorders (CMD, 80 cases). Random indicator method 80 CMD patients divided into two groups, 40 cases in each. Usual treatment group: conventional drugs and CR therapy. EECP treatment group: on the basis of standard treatment group, employ EECP therapy. Comparing the two groups before and after the treatment curative effect cardiac function index, endothelial unction index, adverse cardiovascular events, etc.

After EECP treatment, the treatment group showed a higher effective rate compared to the usual treatment group (P < 0.05). EECP group curative effect, left ventricular ejection fraction,plasma NO and vascular endothelial growth factor levels higher than the usual group, the incidence of adverse cardiovascular events is lower than the usual group. The difference was statistically significant (P < 0.05).

EECP combined with cardiac rehabilitation in patients with CMD symptoms has better effect and safety and provides reference for treatment of CMD patients.

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来源期刊
International heart journal
International heart journal 医学-心血管系统
CiteScore
2.50
自引率
6.70%
发文量
148
审稿时长
6-12 weeks
期刊介绍: Authors of research articles should disclose at the time of submission any financial arrangement they may have with a company whose product figures prominently in the submitted manuscript or with a company making a competing product. Such information will be held in confidence while the paper is under review and will not influence the editorial decision, but if the article is accepted for publication, the editors will usually discuss with the authors the manner in which such information is to be communicated to the reader.
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