复发性转移性低级别浆液性卵巢癌患者对 BRAF 抑制剂单药治疗的持久反应

IF 1.2 Q3 OBSTETRICS & GYNECOLOGY Gynecologic Oncology Reports Pub Date : 2024-05-11 DOI:10.1016/j.gore.2024.101412
Shashank Sama , Sterling Rosqvist , Talicia Savage , Lesley Lomo , Kiera Sibbald , Alli Straubhar , Theresa L. Werner
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引用次数: 0

摘要

晚期低级别浆液性卵巢癌(LGSOC)的全身治疗方案有限。本文报告了一例携带BRAF突变的转移性LGSOC患者,该患者接受了达拉非尼治疗。我们讨论了 LGSOC 的临床、病理和分子特征以及手术注意事项和正在进行的研究。
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Durable response to BRAF inhibitor monotherapy in recurrent metastatic low grade serous ovarian cancer

Low grade serous ovarian cancers (LGSOC) in an advanced setting have limited systemic treatment options. In this paper we report a case of metastatic LGSOC harboring a BRAF mutation, treated with dabrafenib. We discuss the clinical, pathologic and molecular characteristics as well as surgical considerations and ongoing investigations in LGSOC.

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来源期刊
Gynecologic Oncology Reports
Gynecologic Oncology Reports OBSTETRICS & GYNECOLOGY-
CiteScore
2.00
自引率
0.00%
发文量
183
审稿时长
41 days
期刊介绍: Gynecologic Oncology Reports is an online-only, open access journal devoted to the rapid publication of narrative review articles, survey articles, case reports, case series, letters to the editor regarding previously published manuscripts and other short communications in the field of gynecologic oncology. The journal will consider papers that concern tumors of the female reproductive tract, with originality, quality, and clarity the chief criteria of acceptance.
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