用放射疗法治疗的颈静脉鼓室肿瘤:病例报告与文献综述

Aria Shakeri, Anthony Portanova, H. Sakano, Deepinder Pal Singh
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摘要

绒毛膜肿瘤(或副神经节瘤)是一种罕见的神经内分泌源性良性肿瘤,出现在副神经节起源的组织中。由于该肿瘤靠近重要的神经血管结构,因此疾病进展和/或治疗方法可能会造成病态的功能损伤,这给临床治疗带来了巨大挑战。虽然手术仍是此类病例的标准治疗方法,但采用放疗或密切观察进行治疗的趋势日益明显。在此,我们介绍了一例采用容积弧形放射治疗的巨大且形状不规则的壶腹部神经胶质瘤病例。考虑到手术可能导致颅神经病变,放射治疗成为首选治疗方式。该病例证明了容积弧形放射疗法在治疗形状复杂的巨大神经胶质瘤方面的安全性和有效性。
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Glomus jugulotympanicum tumor treated with radiation therapy: A case report with review of literature
Glomus tumors (or paragangliomas) are rare, benign tumors of neuroendocrine origin that appear in tissues of paraganglionic origin. This clinical entity poses a significant treatment challenge due to its proximity to critical neurovascular structures, thus the potential of morbid functional damage caused by disease progression and/or treatment approach. While surgery remains the standard of care for such cases, there has been an increasing trend toward management with radiotherapy or close observation. Here, we present a case of a large and irregularly shaped glomus jugulotympanicum tumor that was treated with volumetric arc radiotherapy. Given the risk of cranial neuropathy with surgery, radiation was the preferred treatment modality. This case demonstrated the safety and efficacy of volumetric arc radiotherapy in the management of a large glomus tumor with a complex shape.
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