Zeyu Liu, Wenjie Dong, Zihao Shi, Jie Pei, Tengfei Ma, Kun Fu
{"title":"三维打印生物仿生珊瑚骨支架在骨缺损修复中的作用机理研究","authors":"Zeyu Liu, Wenjie Dong, Zihao Shi, Jie Pei, Tengfei Ma, Kun Fu","doi":"10.54254/2755-2721/63/20240995","DOIUrl":null,"url":null,"abstract":"With the continuous innovation and development of 3D printing technology, 3D-printed biomimetic coral bone scaffolds have demonstrated significant potential in the field of bone defect repair. This paper aims to explore in-depth the mechanistic study of 3D-printed biomimetic coral bone scaffolds in bone defect repair, by systematically reviewing relevant literature and analyzing their potential mechanisms in promoting bone growth and improving the success rate of bone defect repair. Firstly, this paper introduces the fabrication process and material characteristics of 3D-printed biomimetic coral bone scaffolds. Secondly, the paper discusses the mechanisms of 3D-printed biomimetic coral bone scaffolds in terms of biocompatibility, biomechanical performance, as well as their roles in vascularization and bone formation. Finally, the paper outlines future research directions for 3D-printed biomimetic coral bone scaffolds, including further optimization of material properties, improvement of printing precision, and expansion of clinical applications.","PeriodicalId":350976,"journal":{"name":"Applied and Computational Engineering","volume":" 2","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Mechanistic study on the role of 3D-Printed biomimetic coral bone scaffolds in bone defect repair\",\"authors\":\"Zeyu Liu, Wenjie Dong, Zihao Shi, Jie Pei, Tengfei Ma, Kun Fu\",\"doi\":\"10.54254/2755-2721/63/20240995\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"With the continuous innovation and development of 3D printing technology, 3D-printed biomimetic coral bone scaffolds have demonstrated significant potential in the field of bone defect repair. This paper aims to explore in-depth the mechanistic study of 3D-printed biomimetic coral bone scaffolds in bone defect repair, by systematically reviewing relevant literature and analyzing their potential mechanisms in promoting bone growth and improving the success rate of bone defect repair. Firstly, this paper introduces the fabrication process and material characteristics of 3D-printed biomimetic coral bone scaffolds. Secondly, the paper discusses the mechanisms of 3D-printed biomimetic coral bone scaffolds in terms of biocompatibility, biomechanical performance, as well as their roles in vascularization and bone formation. Finally, the paper outlines future research directions for 3D-printed biomimetic coral bone scaffolds, including further optimization of material properties, improvement of printing precision, and expansion of clinical applications.\",\"PeriodicalId\":350976,\"journal\":{\"name\":\"Applied and Computational Engineering\",\"volume\":\" 2\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-05-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Applied and Computational Engineering\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.54254/2755-2721/63/20240995\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Applied and Computational Engineering","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.54254/2755-2721/63/20240995","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Mechanistic study on the role of 3D-Printed biomimetic coral bone scaffolds in bone defect repair
With the continuous innovation and development of 3D printing technology, 3D-printed biomimetic coral bone scaffolds have demonstrated significant potential in the field of bone defect repair. This paper aims to explore in-depth the mechanistic study of 3D-printed biomimetic coral bone scaffolds in bone defect repair, by systematically reviewing relevant literature and analyzing their potential mechanisms in promoting bone growth and improving the success rate of bone defect repair. Firstly, this paper introduces the fabrication process and material characteristics of 3D-printed biomimetic coral bone scaffolds. Secondly, the paper discusses the mechanisms of 3D-printed biomimetic coral bone scaffolds in terms of biocompatibility, biomechanical performance, as well as their roles in vascularization and bone formation. Finally, the paper outlines future research directions for 3D-printed biomimetic coral bone scaffolds, including further optimization of material properties, improvement of printing precision, and expansion of clinical applications.