在低收入和中等收入国家,食道闭锁的治疗从胸廓切开术过渡到胸腔镜手术

Dr Hansraj Mangray , Dr Sanele Madziba , Dr Yashlin Govender , Dr Trudy Martin , Dr Chantal Rajah , Dr Pieter H Mare , Prof Damian L Clarke
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引用次数: 0

摘要

导言虽然胸腔镜食道闭锁修复术(TEAR)的优点有据可查,但在中低收入国家采用这种方法却遇到了阻力。本研究回顾了南非一家国立三甲医院引进TEAR的单个科室的经验。方法我们介绍了本中心如何为食道闭锁(EA)建立MIS。我们纳入了2016年1月至2022年1月期间在本院接受治疗的所有食道闭锁新生儿。未接受手术或数据缺失的患者被排除在外。我们比较了在我院治疗 C 型 EA 的不同方法。我们使用 Mann-Whitney U 检验对数据进行了分析。其中 54 名患者为 C 型 EA。39 名患者接受了开胸手术以修复缺损,18 名患者接受了 TEAR 手术,其中 16 名患者在胸腔镜下完成了手术。接受TEAR和OEAR(开放式食管闭锁修复术)治疗的两组患者在体重(P值0.035)、胎龄(P值0.002)和手术年龄(P值0.004)方面存在统计学差异。TEAR组和OEAR组的手术时间中位数相差不大,均为20分钟。OEAR 组的死亡率(20.5%)高于 TEAR 组(5.5%),P 值为 0.094。
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Transitioning from thoracotomy to thoracoscopy for esophageal atresia in an LMIC setting

Introduction

Although the benefits of thoracoscopic esophageal atresia repair (TEAR) are well documented, there has been resistance to the uptake of this approach in low- and middle-income countries. This study reviews a single unit's experience introducing TEAR in a South African state sector tertiary hospital.

Method

We describe how we set up MIS for esophageal atresia (EA) at our centre. All neonates with EA managed at our institution from January 2016 to January 2022 were included. Excluded patients included those who were not operated on or if data was missing. We compared the different approaches for managing type C EA in our setting. We analyzed the data using the Mann-Whitney U test.

Results

Sixty-five patients were managed with EA over the study duration. There were 54 patients who had type C EA. Thirty-nine patients underwent thoracotomy to repair the defect, and eighteen underwent TEAR, of which sixteen were completed thoracoscopically. There was a statistically significant difference in weight (p-value 0.035), gestational age (p-value 0.002), and age at operation (p-value 0.004) between the groups treated by TEAR and OEAR (open esophageal atresia repair). There was a small median difference in the operative time between TEAR and OEAR of 20 min. The mortality in the OEAR group was higher (20.5 %) compared to the TEAR group (5.5 %), with a p-value of 0.094.

Conclusion

A dedicated quality improvement program focused on introducing MIS for EA can produce results comparable to the open procedure in an LMIC setting.

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Global pediatrics
Global pediatrics Perinatology, Pediatrics and Child Health
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