全面回顾半胱氨酸在各种代谢紊乱,尤其是心血管疾病、糖尿病、肾功能障碍和缺血性中风中的重要作用。

IF 1.9 4区 生物学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY Current protein & peptide science Pub Date : 2024-01-01 DOI:10.2174/0113892037287215240424090908
Namra Aziz, Pranay Wal, Rishika Sinha, Prashant Ramesh Shirode, GunoSindhu Chakraborthy, Mukesh Chandra Sharma, Pankaj Kumar
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引用次数: 0

摘要

长期以来,代谢紊乱一直是医学专家面临的难题,也是导致成人死亡的主要原因之一。糖尿病、心血管疾病(CVD)、肾功能障碍和缺血性中风是导致全球高死亡率的最常见疾病。活性氧是导致代谢综合征的主要因素之一。所有这些疾病都有各自的治疗方法,在一定程度上可以阻止疾病的病理恶化和不可避免的死亡。然而,它们对人类的健康构成了危险的威胁。半胱氨酸作为一种功能性氨基酸,在预防和治疗心血管疾病、糖尿病、肾功能障碍和缺血性中风等代谢性疾病方面大有可为。在这篇综述中,我们探讨了半胱氨酸能否消除活性氧,进而预防和治疗这些疾病。
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A Comprehensive Review on the Significance of Cysteine in Various Metabolic Disorders; Particularly CVD, Diabetes, Renal Dysfunction, and Ischemic Stroke.

Metabolic disorders have long been a challenge for medical professionals and are a leading cause of mortality in adults. Diabetes, cardiovascular disorders (CVD), renal dysfunction, and ischemic stroke are the most prevalent ailments contributing to a high mortality rate worldwide. Reactive oxygen species are one of the leading factors that act as a fundamental root cause of metabolic syndrome. All of these disorders have their respective treatments, which, to some degree, sabotage the pathological worsening of the disease and an inevitable death. However, they pose a perilous health hazard to humankind. Cysteine, a functional amino acid shows promise for the prevention and treatment of metabolic disorders, such as CVD, Diabetes mellitus, renal dysfunction, and ischemic stroke. In this review, we explored whether cysteine can eradicate reactive oxygen species and subsequently prevent and treat these diseases.

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来源期刊
Current protein & peptide science
Current protein & peptide science 生物-生化与分子生物学
CiteScore
5.20
自引率
0.00%
发文量
73
审稿时长
6 months
期刊介绍: Current Protein & Peptide Science publishes full-length/mini review articles on specific aspects involving proteins, peptides, and interactions between the enzymes, the binding interactions of hormones and their receptors; the properties of transcription factors and other molecules that regulate gene expression; the reactions leading to the immune response; the process of signal transduction; the structure and function of proteins involved in the cytoskeleton and molecular motors; the properties of membrane channels and transporters; and the generation and storage of metabolic energy. In addition, reviews of experimental studies of protein folding and design are given special emphasis. Manuscripts submitted to Current Protein and Peptide Science should cover a field by discussing research from the leading laboratories in a field and should pose questions for future studies. Original papers, research articles and letter articles/short communications are not considered for publication in Current Protein & Peptide Science.
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