肾移植受者身上广泛分布的马约奇肉芽肿。

IF 1 Q4 UROLOGY & NEPHROLOGY CEN Case Reports Pub Date : 2024-05-20 DOI:10.1007/s13730-024-00883-1
Cihan Uysal, Hanife Oguz, Hasan Cifci, Ismail Kocyigit
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引用次数: 0

摘要

肾移植能延长患者的存活时间,提高生活质量,因此是备受鼓励的肾脏替代疗法。遗憾的是,由于长期使用免疫抑制剂,肾移植受者很容易受到感染。尽管皮癣菌感染一般不会危及生命,但最近由于免疫力低下的患者越来越多,皮癣菌感染的临床意义也随之增强。我们介绍了一种罕见的皮癣病--Majocchi 肉芽肿,它在移植后早期扩散到四肢。一名年轻的肾移植受者在移植后早期因急性排斥反应而接受了强化免疫抑制治疗。四个月后,身体各部位出现大量结节性皮损。在皮肤活检中发现了侵袭性真菌感染。组织培养物中也分离出了红色毛癣菌。因此,患者被诊断为马约奇肉芽肿。口服特比萘芬片剂后,治疗效果显著。马约奇肉芽肿是皮肤癣菌病的一种特殊形式,其特点是感染扩散到真皮层。在这个意外的病例中,我们提醒医生注意肾移植受者的机会性感染。
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Widespread form of Majocchi's granuloma in a kidney transplant recipient.

Kidney transplantation is the encouraged kidney replacement therapy due to providing more prolonged survival with a better quality of life. Unfortunately, kidney transplant recipients are susceptible to infections because of long-term utilization of immunosuppression. Despite dermatophyte infections are generally not life-threatening, the clinical significance has been recently enhanced by an increasing number of immunocompromised patients. We have presented a rare dermatophytosis course, Majocchi's granuloma, that spreads to all extremities during the early post-transplant period. A young kidney transplant recipient was exposed to intensive immunosuppression therapy due to acute rejection in the early period of post-transplantation. After four months, numerous nodular skin lesions were raised on various body parts. An invasive fungal infection was identified in the skin biopsy. Also, Trichophyton rubrum was isolated in the tissue cultures. Consequently, the patient was diagnosed with Majocchi's granuloma. An effectual treatment was attained with an oral terbinafine tablet. Majocchi's granuloma is a distinct form of dermatophytosis characterized by the spreading of infection into the dermis. In this unexpected case, we alerted physicians to opportunistic infections in the kidney transplant recipient.

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来源期刊
CEN Case Reports
CEN Case Reports UROLOGY & NEPHROLOGY-
CiteScore
1.90
自引率
0.00%
发文量
80
期刊介绍: Clinical and Experimental Nephrology (CEN) Case Reports is a peer-reviewed online-only journal, officially published biannually by the Japanese Society of Nephrology (JSN).  The journal publishes original case reports in nephrology and related areas.  The purpose of CEN Case Reports is to provide clinicians and researchers with a forum in which to disseminate their personal experience to a wide readership and to review interesting cases encountered by colleagues all over the world, from whom contributions are welcomed.
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