对难治性犬口腔乳头状瘤病的最终放射治疗获得成功。

IF 1.3 2区农林科学 Q2 VETERINARY SCIENCES Veterinary Radiology & Ultrasound Pub Date : 2024-09-01 Epub Date: 2024-05-20 DOI:10.1111/vru.13383

Anett Szczepanek, Judith Bertran, Keijiro Shiomitsu, Lily Thorsen, Jishnu Rao Gutti, Domenico Santoro, Marilia Takada

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引用次数: 0

摘要

本病例报告描述了一只三岁大的雄性边境牧羊犬，它被诊断患有犬乳头状瘤病毒 1 型（CPV-1+）口腔乳头状瘤，对标准治疗方法产生抗药性。随着时间的推移，它出现了与鳞状细胞癌一致的病变。恶性肿瘤被不完全切除，并接受了明确的体外放射治疗（45 Gy，每天 3 Gy × 15）。其余的口腔接受了 27 Gy（1.8 Gy x 15，每天一次）的放射治疗，以治疗播散性口腔乳头状瘤病。由于出现了 3 级粘膜炎，治疗暂时推迟了 2 周。放疗 10 个月后，患者病情仍完全缓解。治疗超过 1 年后，业主没有发现肿瘤复发。

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Successful definitive radiation treatment of refractory canine oral papillomatosis.

This case report describes a three-year-old male intact border collie diagnosed with canine papillomavirus type 1 (CPV-1+) oral papillomas resistant to standard-of-care. With time, he developed lesions consistent with squamous cell carcinoma. Malignant tumors were incompletely excised and treated with definitive external beam radiation therapy (45 Gy, 3 Gy × 15 daily). The remaining oral cavity received 27 Gy (1.8 Gy x 15 daily) to treat the disseminated oral papillomatosis. A temporary treatment delay of 2 weeks was instituted due to grade 3 mucositis. The patient remained in complete remission after 10 months from radiotherapy. No tumor recurrences were noted by the owners after >1 year from treatment.

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来源期刊

Veterinary Radiology & Ultrasound 农林科学-兽医学

CiteScore

2.40

自引率

17.60%

发文量

133

审稿时长

8-16 weeks

期刊介绍： Veterinary Radiology & Ultrasound is a bimonthly, international, peer-reviewed, research journal devoted to the fields of veterinary diagnostic imaging and radiation oncology. Established in 1958, it is owned by the American College of Veterinary Radiology and is also the official journal for six affiliate veterinary organizations. Veterinary Radiology & Ultrasound is represented on the International Committee of Medical Journal Editors, World Association of Medical Editors, and Committee on Publication Ethics. The mission of Veterinary Radiology & Ultrasound is to serve as a leading resource for high quality articles that advance scientific knowledge and standards of clinical practice in the areas of veterinary diagnostic radiology, computed tomography, magnetic resonance imaging, ultrasonography, nuclear imaging, radiation oncology, and interventional radiology. Manuscript types include original investigations, imaging diagnosis reports, review articles, editorials and letters to the Editor. Acceptance criteria include originality, significance, quality, reader interest, composition and adherence to author guidelines.