P.090 第三脑室垂体瘤:病例报告和文献综述

S. Hart, K. Reddy
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摘要

背景介绍脑垂体瘤是一种罕见的低级别肿瘤,通常发生在蝶鞍区。这里我们介绍的是位于第三脑室的垂体细胞瘤。方法:56 岁女性,闭经、高泌乳素血症和进行性位颞侧偏盲。核磁共振成像显示,位于第三脑室的鞍上肿块与垂体分离。手术采用睫状体上和末端平滑肌手术方式切除肿瘤,未发生并发症。术后,她出现了一过性DI,在术后第3天消退,出院时无任何神经功能障碍。病理结果显示为垂体细胞瘤,WHO I 级:垂体细胞瘤是垂体神经上皮细胞产生的罕见肿瘤。大多数病例为单纯蝶鞍或蝶鞍上延伸,或至少与垂体有某种联系。在许多病例中,影像学检查结果与垂体腺瘤相同。我们介绍了一个独特的病例,肿瘤位于鞍上,但似乎与垂体分离。手术干预是预测复发的最重要因素,因为全切是可以治愈的。结论:我们在此介绍一种位置独特的垂体瘤。由于脑垂体瘤极为罕见,其独特的表现和治疗方法有助于更好地了解这种疾病的广泛性。
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P.090 Third ventricular pituicytoma: case report and review of the literature
Background: Pituicytoma is a rare, low grade tumour typically of the sellar region. Here we present a pituicytoma located in the third ventricle. Methods: 56 year old female presented with amenorrhea, hyperprolactinemia, and progressive bitemporal hemianopsia. MRI revealed a suprasellar mass located within the third ventricle and appearing separate from the pituitary. A supraciliary and translamina terminalis surgical approach to tumour resection was completed without complication. Post-operatively, she developed transient DI which resolved by post-opertaive day 3 and she was discharged hoem without any neurological deficits. Pathology revealed pituicytoma, WHO grade I. Results: Pituicytomas are rare tumours arising from neuroepithelial cells of the pituitary. The majority of cases are pure sellar or sellar with suprasellar extension, or at least have some connection to the pituitary. In many cases, imaging findings are synonymous to pituitary adenomas. We present a unique case in which the tumour was suprasellar but appeared separate from the pituitary. Surgical intervention is the most highly predictive factor of recurrence, as gross totoal reseciton can be curable. Conclusions: Here we present a unique location of pituictyoma. Due to the exceedingly rare nature of pituicytoma, unique presentations and management help to provide better understanding of the breadth of this disease presentation.
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