复发缓解型多发性硬化症(RRMS)治疗综述

Arkadiusz Bydliński, Aleksandra Brożyna, Natalia Małek, Sara Emerla, Anita Kwiatkowska, Konrad Karłowicz, Maria Hermanowska, Julia Lubomirska, Patrycja Figurowska, Łukasz Ciulkiewicz, Patryk Pluta
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引用次数: 0

摘要

导言 多发性硬化症(SM)是中枢神经系统最常见的慢性炎症性脱髓鞘疾病。在发病过程中,神经组织受到多处损伤--轴突周围的髓鞘解体。这一过程导致神经纤维的电脉冲传导功能障碍,从而出现各种症状,阻碍患者的功能。 研究目的 本综述旨在总结复发缓解型多发性硬化症(RRMS)的治疗方法。将介绍以下信息:药物类别、作用机制、最重要的副作用及其有效性。材料与方法 本综述介绍了有关复发性-缓解型多发性硬化症(RRMS)治疗的知识现状--它基于 Pubmed 数据库,并使用了有关多发性硬化症问题的关键词。引用文章的选择以最新调查结果为基础。摘要 广泛的治疗方案可让神经科医生准确地治疗患者,但应吸收有关每种物质的基本知识,以选择最佳的个体疗法。多发性硬化症患者的病情各不相同,因此需要因人而异,尽快实施适当的治疗。及早开始治疗可以使患者不丧失日常功能,因为神经退行性病变过程在最初阶段就被阻止了。如果脑组织结构永久性地发生了某些变化,神经科医生应了解对症治疗的方案,以减轻患者的痛苦。
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A review of treatment of relapsing-remitting type of multiple sclerosis (RRMS)
Introduction Multiple sclerosis (SM) is the most common chronic inflammatory-demyelinating disease of the Central Nervous System. In its course, a multifocal damage is done to a nervous tissue - myelin sheaths surrounding axons become disintegrated. This process leads to a dysfunction of the electrical impulses passage along nerve fibers which occurs as various symptoms that hinder the functioning of the patients.  Aim of the study This review aims to summarize treatment methods of relapsing-remitting type of multiple sclerosis (RRMS). Following information will be presented: groups of medications, mechanism of its action, its most important side effects and its effectiveness. Material and method This review presents the current state of knowledge about relapsing-remitting type of multiple sclerosis (RRMS) treatment - it is based on Pubmed database and was carried out using keywords concerning the issues of multiple sclerosis. Cited articles were selected in order to base on up-to-date investigation results. Summary A wide range of therapeutic options let neurologists treat their patients accurately, but the basic knowledge about each substance should be assimilated to choose the best individual therapy. Patients suffering from multiple sclerosis differ from each other and a personal approach is needed to implement appropriate treatment as soon as possible. Early start allows patients to not to lose their everyday functioning areas, as the neurodegenerative process is stopped at the initial stage. If some changes in brain tissue structure are permanently done, neurologists should know the options of symptomatic treatment to alleviate a patient's suffering. 
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