一名多种药物中毒少女的非阻塞性冠状动脉心肌梗死(MINOCA)

Md Moniruzzaman, Amal Krishna Paul, K M Adnan Bulbul, Md Shariful Islam, Md Nahid Hasan
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引用次数: 0

摘要

一名 24 岁的女孩因胸痛、腹部不适和过度睡眠而被送进急诊室。她没有心血管疾病的危险因素。经询问,她曾因情绪激动而服用过房间里的多种药物。她的亲属提供了服用扑热息痛 1000 毫克、头孢拉定 2500 毫克、普萘洛尔 100 毫克、比拉斯汀 160 毫克和羟嗪 200 毫克的病史。事实证明,这些药物在此剂量下均不会导致心肌梗死(MI)。最初的心电图显示为窦性心动过缓,这可能与服用普萘洛尔有关。但入院 2 小时后,她出现了剧烈胸痛,当时的心电图显示为 ST 段压低。发现肌钙蛋白-i升高。经过初步治疗后,进行了冠状动脉造影,结果显示心外膜冠状动脉正常。患者经过对症治疗后完全康复。
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Myocardial infarction in non-obstructive coronary artery (MINOCA) in a young girl with multidrug poisoning
A 24-year-old girl was admitted to the emergency room with chest pain, abdominal discomfort and excessive sleeping tendency after taking some unprescribed medications. She had no risk factors for cardiovascular disease. On query, she gives a history of taking multiple medications available in her room due to some emotional outbreak. Her relatives give a history of taking paracetamol 1000 mg, cephradine 2500 mg, propranolol 100 mg, bilastine 160 mg and hydroxyzine 200 mg. None of these drugs have proven to cause myocardial infarction (MI) at this dosage. Initial ECG showed sinus bradycardia which can be because of taking propranolol. But 2 hours after admission, she developed severe chest pain and at that time ECG showed gross segment (ST) depression. Troponin-i was found to be raised. After initial management, a coronary angiogram was done which revealed normal epicardial coronaries. Patient was managed symptomatically and she recovered completely.
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