利用微波加热催化钌 (II) 直接活化 C-H 并由此形成 C-C/C-N 键的十年进展

Nazia Kausar
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引用次数: 0

摘要

过渡金属催化活化无反应的 C-H 键并随后形成 C-C 键已成为合成有机化学领域的主要和基本工具。另一方面,微波加热技术已被广泛用于进行几乎所有类型的有机转化,并已成为进行合成反应的一种前景广阔的非常规技术。使用钌作为催化剂进行 C-C 键形成反应的直接 C-H 活化是目前的热门话题,它代表了有机化学中一种具有成本效益的合成途径,同时微波辐照还具有缩短反应时间、更环保以及可持续发展的优势。
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A Decade of Advancement in Ruthenium (II)-Catalyzed Direct C-H Activa-tion and Consequent C-C/C-N Bond Formation Using Microwave Heating
Transition-metal catalysed activation of unreactive C-H bonds and subsequent C-C bond formation has emerged as a principal and essential tool in the field of synthetic organic chemistry. On the other hand, the microwave heating technique has been intensively used to carry out organic transformation of almost all kinds and has become a promising non-conventional technique for performing synthetic reactions. Direct C-H activation for C-C bond-forming reactions using ruthe-nium as a catalyst is currently a hot topic and represents a cost-effective synthetic pathway in or-ganic chemistry which is accompanied by the advantages of MW irradiation resulting in shorter reaction time and greener 3 as well as sustainable accomplishments.
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