机械性和非机械性横纹肌溶解并发急性肾损伤的临床病例。病例报告

E. N. Ievlev, Daria R. Bekhtereva, Zukhra R. Khuzina, Edgar K. Chalgubaev, Irina N. Chekmareva
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引用次数: 0

摘要

迄今为止,横纹肌溶解症问题在俄罗斯依然存在。尽管引入了现代诊断、预防和治疗方法,但死亡率仍然很高,高达 40%,尤其是在急性肾损伤的情况下。本文介绍了一个横纹肌溶解症的临床病例,该病例是非创伤性因素(美沙酮、酒精的毒性作用)和创伤性因素(睡眠时的震动和非生理姿势)共同作用的结果。这种综合征最终导致急性肾损伤,直至无尿。在这个临床病例中,进行了强化输液和解毒治疗,包括血液透析程序,从而几乎完全恢复了肾脏的功能状态。因此,根据病史早期诊断横纹肌溶解症和 AKI,及时进行实验室和仪器诊断,可以避免严重的肾脏损伤直至终末尿毒症和致命的后果。
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Clinical case of mechanical and non-mechanical rhabdomyolysis complicated by acute kidney injury. Case report
To date, the problem of rhabdomyolysis remains relevant in Russia. Despite the introduction of modern methods of diagnosis, prevention and treatment, mortality remains high, up to 40%, especially with the addition of acute kidney injury. This article presents a clinical case of rhabdomyolysis, which arose as a result of the combined effects of non-traumatic (toxic effects of methadone, alcohol) and traumatic (vibration and non-physiological position during sleep) factors. This syndrome eventually led to the development of acute kidney damage up to anuria. In this clinical case, intensive infusion and detoxification therapy, including hemodialysis procedures, was carried out, which led to an almost complete restoration of the functional state of the kidneys. Thus, early diagnosis of rhabdomyolysis and AKI based on anamnesis, timely laboratory and instrumental diagnosis can prevent severe kidney damage up to terminal uremia and fatal consequences.
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