A 型肉毒毒素联合物理疗法对痉挛性脑瘫患儿功能能力的影响：随机对照临床试验。

IF 1.7 4区医学 Q3 CLINICAL NEUROLOGY Neurological Research Pub Date : 2024-09-01 Epub Date: 2024-05-26 DOI:10.1080/01616412.2024.2359260

Maria Eliege de Souza, Caroline Razera Ferreira, Claudia Santos Oliveira, Maria Fernanda Molledo Secco, Paulo Fonseca Junior, Paulo Roberto Garcia Lucareli, Daniela Aparecida Biasotto-Gonzalez, Fabiano Politti

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引用次数: 0

摘要

目的调查A型肉毒毒素（BoNT-A）与物理疗法相结合对痉挛性脑瘫（CP）儿童功能能力的影响：24名痉挛性CP患儿接受了BoNT-A和物理治疗或单独物理治疗：讨论：BoNT-A 联合物理疗法与单纯物理疗法对痉挛性 CP 患儿的治疗效果有显著差异（P>0.05）：讨论：BoNT-A 与物理疗法相结合可在治疗开始后的三个月内显著改善 CP 儿童的痉挛和功能。

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Effect of botulinum toxin type a combined with physical therapy on functional capacity in children with spastic cerebral palsy: a randomized controlled clinical trial.

Objective: Investigate the effects of botulinum toxin type A (BoNT-A) combined with physical therapy on functional capacity in children with spastic cerebral palsy (CP).

Methods: Twenty-four children with spastic CP were treated with either BoNT-A and physical therapy or physical therapy alone.

Results: Significant differences (p < 0.05) were found after 30 days of treatment for the Berg Scale, Timed Up and Go (TUG) test, Ashworth Scale and Pediatric Evaluation of Disability Inventory (PEDI) and after three months for the Berg Scale, TUG test and PEDI. No significant differences (p > 0.05) were found in the control group.

Discussion: BoNT-A combined with physical therapy leads to significant improvements in spasticity and functionality in children with CP within a period of three months from the onset of treatment.

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来源期刊

Neurological Research 医学-临床神经学

CiteScore

3.60

自引率

0.00%

发文量

116

审稿时长

5.3 months

期刊介绍： Neurological Research is an international, peer-reviewed journal for reporting both basic and clinical research in the fields of neurosurgery, neurology, neuroengineering and neurosciences. It provides a medium for those who recognize the wider implications of their work and who wish to be informed of the relevant experience of others in related and more distant fields. The scope of the journal includes: •Stem cell applications •Molecular neuroscience •Neuropharmacology •Neuroradiology •Neurochemistry •Biomathematical models •Endovascular neurosurgery •Innovation in neurosurgery.