丙戊酸钠的自闭症风险高于托吡酯和拉莫三嗪

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引用次数: 0

摘要

一项对公共和商业保险参保者进行的队列研究发现,与服用丙戊酸钠相比,产前服用托吡酯或拉莫三嗪可降低儿童患自闭症的风险。在仅限于在妊娠晚期接受药物治疗的妇女的分析中,研究结果基本保持不变。研究结果于2024年3月21/28日发表在《新英格兰医学杂志》上。
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Higher autism risk with valproate than topiramate, lamotrigine

A cohort study examining both publicly and commercially insured individuals has found that prenatal exposure to topiramate or lamotrigine is associated with lower risk of childhood autism compared with exposure to valproate. Study results were largely unchanged in analyses limited to women who received the medications late in pregnancy. Results were published March 21/28, 2024, in The New England Journal of Medicine.

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