驾驭巴基斯坦的免疫格局:进展与陷阱

IF 1.5 Q4 INFECTIOUS DISEASES IJID regions Pub Date : 2024-06-03 DOI:10.1016/j.ijregi.2024.100382
Muhammad Fawad Ashraf , Safi Ur Rehman Daim , Hafsa Fayyaz , Muhammad Aizaz Ashraf , Maham Ashraf
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引用次数: 0

摘要

本研究旨在评估 2022 年巴基斯坦洪灾对受洪灾影响地区疫苗可预防疾病 (VPD) 发病率的影响,特别关注传统上疫苗接种覆盖率较低的地区。设计收集并分析了信德省、开伯尔-普赫图赫瓦省和俾路支省 2021 年 9 月至 11 月和 2022 年 9 月至 11 月的 VPD 每周发病率数据。研究比较了疾病发病率的同比变化,以评估洪灾对疾病负担的影响。结果分析表明,与上一年相比,受洪灾影响地区各种 VPD 的发病率显著增加。百日咳等疾病的报告病例增加了 171%,而流行性腮腺炎的报告病例增加了近 1000%。小儿麻痹症、白喉、新生儿破伤风、麻疹、水痘和风疹等其他疾病的病例数也大幅上升。与此同时,5 岁以下儿童的下呼吸道疾病和腹泻病例也显著增加。研究强调,迫切需要采取有针对性的干预战略,包括加强免疫接种活动和改善脆弱地区的医疗保健基础设施。洪灾后的形势为应对疫苗接种覆盖率方面的现有挑战以及通过全面的公共卫生举措缓解未来的疾病爆发提供了一个重要机会。
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Navigating Pakistan's immunization landscape: Progress and pitfalls

Objectives

This study aims to assess the impact of the 2022 floods in Pakistan on the incidence of vaccine-preventable diseases (VPDs) in flood-affected regions, specifically focusing on areas with traditionally low vaccination coverage.

Design

Weekly incidence data of VPDs from September to November 2021 and 2022 were collected and analyzed for the provinces of Sindh, Khyber Pakhtunkhwa, and Baluchistan. The study compared year-on-year changes in disease incidence to evaluate the effect of the floods on disease burden.

Results

The analysis revealed significant increases in the incidence of various VPDs in the flood-affected regions compared to the previous year. Diseases such as pertussis showed a 171% increase, while mumps exhibited nearly a 1000% increase in reported cases. Other diseases including polio, diphtheria, neonatal tetanus, measles, chickenpox, and rubella also experienced substantial rises in case numbers. Concurrently, cases of lower respiratory tract illnesses and diarrheal diseases in children under five years old surged notably.

Conclusions

The findings underscored the failure of relief and healthcare efforts in managing vaccine-preventable diseases in flood-affected areas of Pakistan. The study highlights an urgent need for targeted intervention strategies, including enhanced immunization drives and healthcare infrastructure improvements in vulnerable regions. The post-flood scenario presents a critical opportunity to address existing challenges in vaccination coverage and to mitigate future disease outbreaks through comprehensive public health initiatives.

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来源期刊
IJID regions
IJID regions Infectious Diseases
CiteScore
1.60
自引率
0.00%
发文量
0
审稿时长
64 days
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