{"title":"表现为肩胛肿块的转移性子宫内膜癌:病例报告和文献综述","authors":"Eccita Rahestyningtyas, Wita Saraswati","doi":"10.1016/j.crwh.2024.e00628","DOIUrl":null,"url":null,"abstract":"<div><p>Bone metastases of endometrial cancers are quite rare, especially in the scapula. Only two previous reports of such cases were found in the literature, and in each case a different approach to diagnosis was used. There are no established recommendations for screening for bone metastases at diagnosis or after initial treatment of endometrial cancers. In the present case, a 55-year-old woman with progressive abdominal distension was diagnosed with a cystic mass. Histopathological analysis revealed grade II synchronous endometrioid carcinoma in both the endometrium and the ovaries. The patient received three cycles of combined paclitaxel and carboplatin chemotherapy. Seven months after the last chemotherapy cycle, a palpable lump was found in the right shoulder, suggesting a lesion in the right scapula. A bone scan revealed heightened radioactivity uptake, highlighting the unpredictable nature of the disease progression. The choice of diagnostic imaging modality remains challenging. This case emphasises the need for ongoing investigation of the mechanisms of distant metastasis and for the development of standardised diagnostic and therapeutic strategies.</p></div>","PeriodicalId":9657,"journal":{"name":"Case Reports in Women's Health","volume":"42 ","pages":"Article e00628"},"PeriodicalIF":0.7000,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214911224000493/pdfft?md5=eec03a1b1887dcbe191d49dbf0817c34&pid=1-s2.0-S2214911224000493-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Metastatic endometrial carcinoma presenting as a scapular mass: A case report and literature review\",\"authors\":\"Eccita Rahestyningtyas, Wita Saraswati\",\"doi\":\"10.1016/j.crwh.2024.e00628\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Bone metastases of endometrial cancers are quite rare, especially in the scapula. Only two previous reports of such cases were found in the literature, and in each case a different approach to diagnosis was used. There are no established recommendations for screening for bone metastases at diagnosis or after initial treatment of endometrial cancers. In the present case, a 55-year-old woman with progressive abdominal distension was diagnosed with a cystic mass. Histopathological analysis revealed grade II synchronous endometrioid carcinoma in both the endometrium and the ovaries. The patient received three cycles of combined paclitaxel and carboplatin chemotherapy. Seven months after the last chemotherapy cycle, a palpable lump was found in the right shoulder, suggesting a lesion in the right scapula. A bone scan revealed heightened radioactivity uptake, highlighting the unpredictable nature of the disease progression. The choice of diagnostic imaging modality remains challenging. This case emphasises the need for ongoing investigation of the mechanisms of distant metastasis and for the development of standardised diagnostic and therapeutic strategies.</p></div>\",\"PeriodicalId\":9657,\"journal\":{\"name\":\"Case Reports in Women's Health\",\"volume\":\"42 \",\"pages\":\"Article e00628\"},\"PeriodicalIF\":0.7000,\"publicationDate\":\"2024-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2214911224000493/pdfft?md5=eec03a1b1887dcbe191d49dbf0817c34&pid=1-s2.0-S2214911224000493-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Case Reports in Women's Health\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2214911224000493\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"OBSTETRICS & GYNECOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Case Reports in Women's Health","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2214911224000493","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}
引用次数: 0
摘要
子宫内膜癌的骨转移非常罕见,尤其是在肩胛骨。文献中仅发现过两例此类病例,而且每例都采用了不同的诊断方法。目前还没有关于子宫内膜癌诊断时或初始治疗后骨转移筛查的建议。在本病例中,一名 55 岁的妇女因进行性腹胀被诊断为囊性肿块。组织病理分析表明,子宫内膜和卵巢中均存在 II 级同步性子宫内膜样癌。患者接受了三个周期的紫杉醇和卡铂联合化疗。最后一个化疗周期结束后七个月,患者右肩发现一个可触及的肿块,提示右肩胛骨有病变。骨扫描显示放射性摄取增加,突显了疾病进展的不可预测性。诊断成像方式的选择仍然具有挑战性。本病例强调了对远处转移机制进行持续调查以及制定标准化诊断和治疗策略的必要性。
Metastatic endometrial carcinoma presenting as a scapular mass: A case report and literature review
Bone metastases of endometrial cancers are quite rare, especially in the scapula. Only two previous reports of such cases were found in the literature, and in each case a different approach to diagnosis was used. There are no established recommendations for screening for bone metastases at diagnosis or after initial treatment of endometrial cancers. In the present case, a 55-year-old woman with progressive abdominal distension was diagnosed with a cystic mass. Histopathological analysis revealed grade II synchronous endometrioid carcinoma in both the endometrium and the ovaries. The patient received three cycles of combined paclitaxel and carboplatin chemotherapy. Seven months after the last chemotherapy cycle, a palpable lump was found in the right shoulder, suggesting a lesion in the right scapula. A bone scan revealed heightened radioactivity uptake, highlighting the unpredictable nature of the disease progression. The choice of diagnostic imaging modality remains challenging. This case emphasises the need for ongoing investigation of the mechanisms of distant metastasis and for the development of standardised diagnostic and therapeutic strategies.